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A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma.
Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI. Laks DR, et al. Neuro Oncol. 2018 May 18;20(6):764-775. doi: 10.1093/neuonc/nox215. Neuro Oncol. 2018. PMID: 29136244 Free PMC article.
Large-scale assessment of the gliomasphere model system.
Laks DR, Crisman TJ, Shih MY, Mottahedeh J, Gao F, Sperry J, Garrett MC, Yong WH, Cloughesy TF, Liau LM, Lai A, Coppola G, Kornblum HI. Laks DR, et al. Neuro Oncol. 2016 Oct;18(10):1367-78. doi: 10.1093/neuonc/now045. Epub 2016 Apr 25. Neuro Oncol. 2016. PMID: 27116978 Free PMC article.
Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway.
Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, Wexler E, Saigusa K, Nakamura Y, Laks DR, Mischel PS, Viapiano M, Kornblum HI. Nakano I, et al. Among authors: laks dr. Neuro Oncol. 2011 Jun;13(6):622-34. doi: 10.1093/neuonc/nor023. Epub 2011 May 9. Neuro Oncol. 2011. PMID: 21558073 Free PMC article.
A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.
Ghochani Y, Muthukrishnan SD, Sohrabi A, Kawaguchi R, Condro MC, Bastola S, Gao F, Qin Y, Mottahedeh J, Iruela-Arispe ML, Rao N, Laks DR, Liau LM, Mathern GW, Goldman SA, Carmichael ST, Nakano I, Coppola G, Seidlits SK, Kornblum HI. Ghochani Y, et al. Among authors: laks dr. Cell Rep. 2022 Oct 18;41(3):111511. doi: 10.1016/j.celrep.2022.111511. Cell Rep. 2022. PMID: 36261010 Free PMC article.
Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.
Alvarado AG, Tessema K, Muthukrishnan SD, Sober M, Kawaguchi R, Laks DR, Bhaduri A, Swarup V, Nathanson DA, Geschwind DH, Goldman SA, Kornblum HI. Alvarado AG, et al. Among authors: laks dr. Cancer Res Commun. 2022 Sep;2(9):1049-1060. doi: 10.1158/2767-9764.crc-22-0003. Epub 2022 Sep 22. Cancer Res Commun. 2022. PMID: 36213002 Free PMC article.
24 results