Lai KKY - Search Results

1

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer.

Manegold P, Lai KKY, Wu Y, Teo JL, Lenz HJ, Genyk YS, Pandol SJ, Wu K, Lin DP, Chen Y, Nguyen C, Zhao Y, Kahn M. Manegold P, et al. Among authors: lai kky. Cancers (Basel). 2018 Mar 29;10(4):95. doi: 10.3390/cancers10040095. Cancers (Basel). 2018. PMID: 29596326 Free PMC article.

2

Nuclear receptor/Wnt beta-catenin interactions are regulated via differential CBP/p300 coactivator usage.

Ono M, Lai KKY, Wu K, Nguyen C, Lin DP, Murali R, Kahn M. Ono M, et al. Among authors: lai kky. PLoS One. 2018 Jul 18;13(7):e0200714. doi: 10.1371/journal.pone.0200714. eCollection 2018. PLoS One. 2018. PMID: 30020971 Free PMC article.

3

Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.

Lai KKY, Nguyen C, Lee KS, Lee A, Lin DP, Teo JL, Kahn M. Lai KKY, et al. Curr Mol Pharmacol. 2019;12(3):167-183. doi: 10.2174/1874467212666190304121131. Curr Mol Pharmacol. 2019. PMID: 30836930 Free PMC article.

4

Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer.

Saloman JL, Albers KM, Cruz-Monserrate Z, Davis BM, Edderkaoui M, Eibl G, Epouhe AY, Gedeon JY, Gorelick FS, Grippo PJ, Groblewski GE, Husain SZ, Lai KKY, Pandol SJ, Uc A, Wen L, Whitcomb DC. Saloman JL, et al. Among authors: lai kky. Pancreas. 2019 Jul;48(6):759-779. doi: 10.1097/MPA.0000000000001335. Pancreas. 2019. PMID: 31206467 Free PMC article. Review.

5

The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300.

Lukaszewicz AI, Nguyen C, Melendez E, Lin DP, Teo JL, Lai KKY, Huttner WB, Shi SH, Kahn M. Lukaszewicz AI, et al. Among authors: lai kky. Cancers (Basel). 2019 Jul 9;11(7):962. doi: 10.3390/cancers11070962. Cancers (Basel). 2019. PMID: 31324005 Free PMC article.

6

Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.

Asahina K, Balog S, Hwang E, Moon E, Wan E, Skrypek K, Chen Y, Fernandez J, Romo J, Yang Q, Lai K, French SW, Tsukamoto H. Asahina K, et al. Am J Physiol Gastrointest Liver Physiol. 2020 Feb 1;318(2):G265-G276. doi: 10.1152/ajpgi.00218.2019. Epub 2019 Nov 25. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 31760766 Free PMC article.

7

Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells.

Che M, Kweon SM, Teo JL, Yuan YC, Melstrom LG, Waldron RT, Lugea A, Urrutia RA, Pandol SJ, Lai KKY. Che M, et al. Among authors: lai kky. Cancers (Basel). 2020 Jun 5;12(6):1476. doi: 10.3390/cancers12061476. Cancers (Basel). 2020. PMID: 32516943 Free PMC article.

8

p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair.

Lai KKY, Hu X, Chosa K, Nguyen C, Lin DP, Lai KK, Kato N, Higuchi Y, Highlander SK, Melendez E, Eriguchi Y, Fueger PT, Ouellette AJ, Chimge NO, Ono M, Kahn M. Lai KKY, et al. Cancers (Basel). 2021 Mar 14;13(6):1288. doi: 10.3390/cancers13061288. Cancers (Basel). 2021. PMID: 33799418 Free PMC article.

9

Pharmacologically Targeting the WNT/β-Catenin Signaling Cascade: Avoiding the Sword of Damocles.

Lai KKY, Kahn M. Lai KKY, et al. Handb Exp Pharmacol. 2021;269:383-422. doi: 10.1007/164_2021_523. Handb Exp Pharmacol. 2021. PMID: 34463849

10

Differential Kat3 Usage Orchestrates the Integration of Cellular Metabolism with Differentiation.

Hu X, Ono M, Chimge NO, Chosa K, Nguyen C, Melendez E, Lou CH, Lim P, Termini J, Lai KKY, Fueger PT, Teo JL, Higuchi Y, Kahn M. Hu X, et al. Among authors: lai kky. Cancers (Basel). 2021 Nov 23;13(23):5884. doi: 10.3390/cancers13235884. Cancers (Basel). 2021. PMID: 34884992 Free PMC article.

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