Lai J - Search Results

1

Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia.

White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo-Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. White JA, et al. Among authors: lai j. J Clin Invest. 2023 Mar 15;133(6):e165245. doi: 10.1172/JCI165245. J Clin Invest. 2023. PMID: 36602866 Free PMC article.

2

Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors.

Blankson JN, Bailey JR, Thayil S, Yang HC, Lassen K, Lai J, Gandhi SK, Siliciano JD, Williams TM, Siliciano RF. Blankson JN, et al. Among authors: lai j. J Virol. 2007 Mar;81(5):2508-18. doi: 10.1128/JVI.02165-06. Epub 2006 Dec 6. J Virol. 2007. PMID: 17151109 Free PMC article.

3

Stability of the latent reservoir for HIV-1 in patients receiving valproic acid.

Siliciano JD, Lai J, Callender M, Pitt E, Zhang H, Margolick JB, Gallant JE, Cofrancesco J Jr, Moore RD, Gange SJ, Siliciano RF. Siliciano JD, et al. Among authors: lai j. J Infect Dis. 2007 Mar 15;195(6):833-6. doi: 10.1086/511823. Epub 2007 Jan 30. J Infect Dis. 2007. PMID: 17299713

4

The role of protective HCP5 and HLA-C associated polymorphisms in the control of HIV-1 replication in a subset of elite suppressors.

Han Y, Lai J, Barditch-Crovo P, Gallant JE, Williams TM, Siliciano RF, Blankson JN. Han Y, et al. Among authors: lai j. AIDS. 2008 Feb 19;22(4):541-4. doi: 10.1097/QAD.0b013e3282f470e4. AIDS. 2008. PMID: 18301071

5

The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation.

McMahon MA, Siliciano JD, Lai J, Liu JO, Stivers JT, Siliciano RF, Kohli RM. McMahon MA, et al. Among authors: lai j. J Biol Chem. 2008 Nov 14;283(46):31289-93. doi: 10.1074/jbc.C800188200. Epub 2008 Sep 24. J Biol Chem. 2008. PMID: 18818198 Free PMC article.

6

A critical subset model provides a conceptual basis for the high antiviral activity of major HIV drugs.

Shen L, Rabi SA, Sedaghat AR, Shan L, Lai J, Xing S, Siliciano RF. Shen L, et al. Among authors: lai j. Sci Transl Med. 2011 Jul 13;3(91):91ra63. doi: 10.1126/scitranslmed.3002304. Sci Transl Med. 2011. PMID: 21753122 Free PMC article.

7

HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy.

Durand CM, Ghiaur G, Siliciano JD, Rabi SA, Eisele EE, Salgado M, Shan L, Lai JF, Zhang H, Margolick J, Jones RJ, Gallant JE, Ambinder RF, Siliciano RF. Durand CM, et al. Among authors: lai jf. J Infect Dis. 2012 Mar 15;205(6):1014-8. doi: 10.1093/infdis/jir884. Epub 2012 Jan 24. J Infect Dis. 2012. PMID: 22275402 Free PMC article.

8

A quantitative basis for antiretroviral therapy for HIV-1 infection.

Jilek BL, Zarr M, Sampah ME, Rabi SA, Bullen CK, Lai J, Shen L, Siliciano RF. Jilek BL, et al. Among authors: lai j. Nat Med. 2012 Feb 19;18(3):446-51. doi: 10.1038/nm.2649. Nat Med. 2012. PMID: 22344296 Free PMC article.

9

Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay.

Laird GM, Eisele EE, Rabi SA, Lai J, Chioma S, Blankson JN, Siliciano JD, Siliciano RF. Laird GM, et al. Among authors: lai j. PLoS Pathog. 2013;9(5):e1003398. doi: 10.1371/journal.ppat.1003398. Epub 2013 May 30. PLoS Pathog. 2013. PMID: 23737751 Free PMC article. Clinical Trial.

10

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

Ho YC, Shan L, Hosmane NN, Wang J, Laskey SB, Rosenbloom DI, Lai J, Blankson JN, Siliciano JD, Siliciano RF. Ho YC, et al. Among authors: lai j. Cell. 2013 Oct 24;155(3):540-51. doi: 10.1016/j.cell.2013.09.020. Epub 2013 Oct 24. Cell. 2013. PMID: 24243014 Free PMC article.

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