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Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: lagarrigue s. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
A factor model to analyze heterogeneity in gene expression.
Blum Y, Le Mignon G, Lagarrigue S, Causeur D. Blum Y, et al. Among authors: lagarrigue s. BMC Bioinformatics. 2010 Jul 2;11:368. doi: 10.1186/1471-2105-11-368. BMC Bioinformatics. 2010. PMID: 20598132 Free PMC article.
Regulation of LPCAT3 by LXR.
Demeure O, Lecerf F, Duby C, Desert C, Ducheix S, Guillou H, Lagarrigue S. Demeure O, et al. Among authors: lagarrigue s. Gene. 2011 Jan 1;470(1-2):7-11. doi: 10.1016/j.gene.2010.09.002. Epub 2010 Sep 15. Gene. 2011. PMID: 20837115
Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.
Roux PF, Boitard S, Blum Y, Parks B, Montagner A, Mouisel E, Djari A, Esquerré D, Désert C, Boutin M, Leroux S, Lecerf F, Le Bihan-Duval E, Klopp C, Servin B, Pitel F, Duclos MJ, Guillou H, Lusis AJ, Demeure O, Lagarrigue S. Roux PF, et al. Among authors: lagarrigue s. G3 (Bethesda). 2015 Feb 3;5(4):517-29. doi: 10.1534/g3.115.016865. G3 (Bethesda). 2015. PMID: 25653314 Free PMC article.
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.
Montagner A, Polizzi A, Fouché E, Ducheix S, Lippi Y, Lasserre F, Barquissau V, Régnier M, Lukowicz C, Benhamed F, Iroz A, Bertrand-Michel J, Al Saati T, Cano P, Mselli-Lakhal L, Mithieux G, Rajas F, Lagarrigue S, Pineau T, Loiseau N, Postic C, Langin D, Wahli W, Guillou H. Montagner A, et al. Among authors: lagarrigue s. Gut. 2016 Jul;65(7):1202-14. doi: 10.1136/gutjnl-2015-310798. Epub 2016 Feb 1. Gut. 2016. PMID: 26838599 Free PMC article.
Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals.
Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin R, Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Montagner A, et al. Among authors: lagarrigue s. Sci Rep. 2016 Feb 16;6:20127. doi: 10.1038/srep20127. Sci Rep. 2016. PMID: 26879573 Free PMC article.
Erratum: Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals.
Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin R, Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Montagner A, et al. Among authors: lagarrigue s. Sci Rep. 2016 Apr 20;6:23951. doi: 10.1038/srep23951. Sci Rep. 2016. PMID: 27094712 Free PMC article. No abstract available.
Multi-tissue transcriptomic study reveals the main role of liver in the chicken adaptive response to a switch in dietary energy source through the transcriptional regulation of lipogenesis.
Desert C, Baéza E, Aite M, Boutin M, Le Cam A, Montfort J, Houee-Bigot M, Blum Y, Roux PF, Hennequet-Antier C, Berri C, Metayer-Coustard S, Collin A, Allais S, Le Bihan E, Causeur D, Gondret F, Duclos MJ, Lagarrigue S. Desert C, et al. Among authors: lagarrigue s. BMC Genomics. 2018 Mar 7;19(1):187. doi: 10.1186/s12864-018-4520-5. BMC Genomics. 2018. PMID: 29514634 Free PMC article.
98 results