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Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.
Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P. Meng J, et al. Among authors: lafon pa. Nat Chem Biol. 2022 Aug;18(8):894-903. doi: 10.1038/s41589-022-01050-2. Epub 2022 Jun 9. Nat Chem Biol. 2022. PMID: 35681029 Free article.
TrkB receptor interacts with mGlu2 receptor and mediates antipsychotic-like effects of mGlu2 receptor activation in the mouse.
Philibert CE, Disdier C, Lafon PA, Bouyssou A, Oosterlaken M, Galant S, Pizzoccaro A, Tuduri P, Ster J, Liu J, Kniazeff J, Pin JP, Rondard P, Marin P, Vandermoere F. Philibert CE, et al. Among authors: lafon pa. Sci Adv. 2024 Jan 26;10(4):eadg1679. doi: 10.1126/sciadv.adg1679. Epub 2024 Jan 26. Sci Adv. 2024. PMID: 38277461 Free PMC article.
Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates.
Wang Y, Lafon PA, Salvador-Prince L, Gines AR, Trousse F, Torrent J, Prevostel C, Crozet C, Liu J, Perrier V. Wang Y, et al. Among authors: lafon pa. Environ Res. 2021 Apr;195:110829. doi: 10.1016/j.envres.2021.110829. Epub 2021 Feb 4. Environ Res. 2021. PMID: 33548298 Free article.
Low doses of bioherbicide favour prion aggregation and propagation in vivo.
Lafon PA, Imberdis T, Wang Y, Torrent J, Robitzer M, Huetter E, Alvarez-Martinez MT, Chevallier N, Givalois L, Desrumaux C, Liu J, Perrier V. Lafon PA, et al. Sci Rep. 2018 May 23;8(1):8023. doi: 10.1038/s41598-018-25966-9. Sci Rep. 2018. PMID: 29795181 Free PMC article.
Plasma cholesterol level determines in vivo prion propagation.
Perrier V, Imberdis T, Lafon PA, Cefis M, Wang Y, Huetter E, Arnaud JD, Alvarez-Martinez T, Le Guern N, Maquart G, Lagrost L, Desrumaux C. Perrier V, et al. Among authors: lafon pa. J Lipid Res. 2017 Oct;58(10):1950-1961. doi: 10.1194/jlr.M073718. Epub 2017 Aug 1. J Lipid Res. 2017. PMID: 28765208 Free PMC article.