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Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.
Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJ. Henpita C, et al. Among authors: ladiges w. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. Aging Cell. 2023. PMID: 36734200 Free PMC article.
Fisetin is a senotherapeutic that extends health and lifespan.
Yousefzadeh MJ, Zhu Y, McGowan SJ, Angelini L, Fuhrmann-Stroissnigg H, Xu M, Ling YY, Melos KI, Pirtskhalava T, Inman CL, McGuckian C, Wade EA, Kato JI, Grassi D, Wentworth M, Burd CE, Arriaga EA, Ladiges WL, Tchkonia T, Kirkland JL, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. EBioMedicine. 2018 Oct;36:18-28. doi: 10.1016/j.ebiom.2018.09.015. Epub 2018 Sep 29. EBioMedicine. 2018. PMID: 30279143 Free PMC article.
Molecular pathology endpoints useful for aging studies.
Niedernhofer LJ, Kirkland JL, Ladiges W. Niedernhofer LJ, et al. Among authors: ladiges w. Ageing Res Rev. 2017 May;35:241-249. doi: 10.1016/j.arr.2016.09.012. Epub 2016 Oct 6. Ageing Res Rev. 2017. PMID: 27721062 Free PMC article. Review.
Is aging "normal"?
Johnson C, Ladiges W. Johnson C, et al. Among authors: ladiges w. Aging Pathobiol Ther. 2022;4(4):98-99. Epub 2022 Dec 29. Aging Pathobiol Ther. 2022. PMID: 36644127 Free PMC article.
Sex Matters in Aging. The Canagliflozin Story.
Wezeman J, Ladiges W. Wezeman J, et al. Among authors: ladiges w. Aging Pathobiol Ther. 2022;4(3):84-86. doi: 10.31491/apt.2022.09.091. Epub 2022 Sep 30. Aging Pathobiol Ther. 2022. PMID: 36540066 Free PMC article.
195 results