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Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Halby L, Menon Y, Rilova E, Pechalrieu D, Masson V, Faux C, Bouhlel MA, David-Cordonnier MH, Novosad N, Aussagues Y, Samson A, Lacroix L, Ausseil F, Fleury L, Guianvarc'h D, Ferroud C, Arimondo PB. Halby L, et al. Among authors: lacroix l. J Med Chem. 2017 Jun 8;60(11):4665-4679. doi: 10.1021/acs.jmedchem.7b00176. Epub 2017 May 23. J Med Chem. 2017. PMID: 28463515
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.
Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, Hoarau M, Arimondo PB, Vigneron JP, Lehn JM, Riou JF, Garestier T, Hélène C. Mergny JL, et al. Among authors: lacroix l. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3062-7. doi: 10.1073/pnas.051620698. Proc Natl Acad Sci U S A. 2001. PMID: 11248032 Free PMC article.
Unusual DNA conformations: implications for telomeres.
Mills M, Lacroix L, Arimondo PB, Leroy JL, François JC, Klump H, Mergny JL. Mills M, et al. Among authors: lacroix l. Curr Med Chem Anticancer Agents. 2002 Sep;2(5):627-44. doi: 10.2174/1568011023353877. Curr Med Chem Anticancer Agents. 2002. PMID: 12678729 Review.
New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.
Gros C, Fleury L, Nahoum V, Faux C, Valente S, Labella D, Cantagrel F, Rilova E, Bouhlel MA, David-Cordonnier MH, Dufau I, Ausseil F, Mai A, Mourey L, Lacroix L, Arimondo PB. Gros C, et al. Among authors: lacroix l. J Biol Chem. 2015 Mar 6;290(10):6293-302. doi: 10.1074/jbc.M114.594671. Epub 2014 Dec 18. J Biol Chem. 2015. PMID: 25525263 Free PMC article.
Nucleic acids as targets for antitelomerase agents.
Alberti P, Lacroix L, Guittat L, Hélène C, Mergny JL. Alberti P, et al. Among authors: lacroix l. Mini Rev Med Chem. 2003 Feb;3(1):23-36. doi: 10.2174/1389557033405485. Mini Rev Med Chem. 2003. PMID: 12570852 Review.
DNA nanomachines and nanostructures involving quadruplexes.
Alberti P, Bourdoncle A, Saccà B, Lacroix L, Mergny JL. Alberti P, et al. Among authors: lacroix l. Org Biomol Chem. 2006 Sep 21;4(18):3383-91. doi: 10.1039/b605739j. Epub 2006 Jun 22. Org Biomol Chem. 2006. PMID: 17036128
Fluorescence-based melting assays for studying quadruplex ligands.
De Cian A, Guittat L, Kaiser M, Saccà B, Amrane S, Bourdoncle A, Alberti P, Teulade-Fichou MP, Lacroix L, Mergny JL. De Cian A, et al. Among authors: lacroix l. Methods. 2007 Jun;42(2):183-95. doi: 10.1016/j.ymeth.2006.10.004. Methods. 2007. PMID: 17472900 Review.
502 results