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EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.
Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, Reißig S, Lacher SM, Reichhold C, Mufazalov IA, Ben-Nun A, Kuhlmann T, Wettschureck N, Sailer AW, Rajewsky K, Casola S, Waisman A, Kurschus FC. Wanke F, et al. Among authors: lacher sm. Cell Rep. 2017 Jan 31;18(5):1270-1284. doi: 10.1016/j.celrep.2017.01.020. Cell Rep. 2017. PMID: 28147280 Free article.
NG2 plays a role in neuroinflammation but is not expressed by immune cells.
Kitic M, Karram K, Israel N, Yogev N, Lacher SM, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus FC, Waisman A. Kitic M, et al. Among authors: lacher sm. Acta Neuropathol. 2017 Aug;134(2):325-327. doi: 10.1007/s00401-017-1735-5. Epub 2017 May 31. Acta Neuropathol. 2017. PMID: 28567522 No abstract available.
Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.
Timilshina M, You Z, Lacher SM, Acharya S, Jiang L, Kang Y, Kim JA, Chang HW, Kim KJ, Park B, Song JH, Ko HJ, Park YY, Ma MJ, Nepal MR, Jeong TC, Chung Y, Waisman A, Chang JH. Timilshina M, et al. Among authors: lacher sm. Cell Rep. 2019 Jun 4;27(10):2948-2961.e7. doi: 10.1016/j.celrep.2019.05.020. Cell Rep. 2019. PMID: 31167140 Free article.
Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology.
Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Härtner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. Mohebiany AN, et al. Among authors: lacher sm. Cell Rep. 2020 Feb 4;30(5):1585-1597.e6. doi: 10.1016/j.celrep.2019.12.097. Cell Rep. 2020. PMID: 32023471 Free article.
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.
Brüstle A, Brenner D, Knobbe CB, Lang PA, Virtanen C, Hershenfield BM, Reardon C, Lacher SM, Ruland J, Ohashi PS, Mak TW. Brüstle A, et al. Among authors: lacher sm. J Clin Invest. 2012 Dec;122(12):4698-709. doi: 10.1172/JCI63528. Epub 2012 Nov 1. J Clin Invest. 2012. PMID: 23114599 Free PMC article.
CD33 BiTE® molecule-mediated immune synapse formation and subsequent T-cell activation is determined by the expression profile of activating and inhibitory checkpoint molecules on AML cells.
Marcinek A, Brauchle B, Rohrbacher L, Hänel G, Philipp N, Märkl F, Strzalkowski T, Lacher SM, Udiljak D, Spiekermann K, Theurich S, Kobold S, Kischel R, James JR, Bücklein VL, Subklewe M. Marcinek A, et al. Among authors: lacher sm. Cancer Immunol Immunother. 2023 Jul;72(7):2499-2512. doi: 10.1007/s00262-023-03439-x. Epub 2023 Apr 11. Cancer Immunol Immunother. 2023. PMID: 37041225 Free PMC article.
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