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ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome.
Rodríguez-Ruiz L, Lozano-Gil JM, Naranjo-Sánchez E, Martínez-Balsalobre E, Martínez-López A, Lachaud C, Blanquer M, Phung TK, García-Moreno D, Cayuela ML, Tyrkalska SD, Pérez-Oliva AB, Mulero V. Rodríguez-Ruiz L, et al. Among authors: lachaud c. EMBO Mol Med. 2023 Oct 11;15(10):e18142. doi: 10.15252/emmm.202318142. Epub 2023 Sep 7. EMBO Mol Med. 2023. PMID: 37675820 Free PMC article.
Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1.
Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, Cayuela ML, García-Moreno D, Mulero V. Tyrkalska SD, et al. Among authors: lachaud c. Immunity. 2019 Jul 16;51(1):50-63.e5. doi: 10.1016/j.immuni.2019.05.005. Epub 2019 Jun 4. Immunity. 2019. PMID: 31174991 Free PMC article.
Zebrafish Models to Study Inflammasome-Mediated Regulation of Hematopoiesis.
Rodríguez-Ruiz L, Lozano-Gil JM, Lachaud C, Mesa-Del-Castillo P, Cayuela ML, García-Moreno D, Pérez-Oliva AB, Mulero V. Rodríguez-Ruiz L, et al. Among authors: lachaud c. Trends Immunol. 2020 Dec;41(12):1116-1127. doi: 10.1016/j.it.2020.10.006. Epub 2020 Nov 5. Trends Immunol. 2020. PMID: 33162327 Free article. Review.
A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.
Berrada S, Martínez-Balsalobre E, Larcher L, Azzoni V, Vasquez N, Da Costa M, Abel S, Audoly G, Lee L, Montersino C, Castellano R, Combes S, Gelot C, Ceccaldi R, Guervilly JH, Soulier J, Lachaud C. Berrada S, et al. Among authors: lachaud c. Nucleic Acids Res. 2023 Aug 25;51(15):7988-8004. doi: 10.1093/nar/gkad559. Nucleic Acids Res. 2023. PMID: 37395445 Free PMC article.
mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.
Lipskaia L, Breau M, Cayrou C, Churikov D, Braud L, Jacquet J, Born E, Fouillade C, Curras-Alonso S, Bauwens S, Jourquin F, Fiore F, Castellano R, Josselin E, Sánchez-Ferrer C, Giovinazzo G, Lachaud C, Gilson E, Flores I, Londono-Vallejo A, Adnot S, Géli V. Lipskaia L, et al. Among authors: lachaud c. EMBO Rep. 2024 Mar;25(3):1650-1684. doi: 10.1038/s44319-023-00041-1. Epub 2024 Feb 29. EMBO Rep. 2024. PMID: 38424230 Free PMC article.
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