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Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M. Bogie J, et al. Among authors: lutjohann d. Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4. Sci Rep. 2019. PMID: 30894635 Free PMC article.
Dietary plant sterols accumulate in the brain.
Jansen PJ, Lütjohann D, Abildayeva K, Vanmierlo T, Plösch T, Plat J, von Bergmann K, Groen AK, Ramaekers FC, Kuipers F, Mulder M. Jansen PJ, et al. Among authors: lutjohann d. Biochim Biophys Acta. 2006 Apr;1761(4):445-53. doi: 10.1016/j.bbalip.2006.03.015. Epub 2006 Apr 19. Biochim Biophys Acta. 2006. PMID: 16677856
Human apolipoprotein C-I expression in mice impairs learning and memory functions.
Abildayeva K, Berbée JF, Blokland A, Jansen PJ, Hoek FJ, Meijer O, Lütjohann D, Gautier T, Pillot T, De Vente J, Havekes LM, Ramaekers FC, Kuipers F, Rensen PC, Mulder M. Abildayeva K, et al. Among authors: lutjohann d. J Lipid Res. 2008 Apr;49(4):856-69. doi: 10.1194/jlr.M700518-JLR200. Epub 2007 Dec 26. J Lipid Res. 2008. PMID: 18160739 Free article.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. Among authors: lutjohann d. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.
Liver X receptor activation restores memory in aged AD mice without reducing amyloid.
Vanmierlo T, Rutten K, Dederen J, Bloks VW, van Vark-van der Zee LC, Kuipers F, Kiliaan A, Blokland A, Sijbrands EJ, Steinbusch H, Prickaerts J, Lütjohann D, Mulder M. Vanmierlo T, et al. Among authors: lutjohann d. Neurobiol Aging. 2011 Jul;32(7):1262-72. doi: 10.1016/j.neurobiolaging.2009.07.005. Epub 2009 Aug 11. Neurobiol Aging. 2011. PMID: 19674815
410 results