Löscher W - Search Results

1

A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood-brain barrier models for drug transport studies.

Gericke B, Römermann K, Noack A, Noack S, Kronenberg J, Blasig IE, Löscher W. Gericke B, et al. Among authors: loscher w. Fluids Barriers CNS. 2020 Aug 26;17(1):53. doi: 10.1186/s12987-020-00212-5. Fluids Barriers CNS. 2020. PMID: 32843059 Free PMC article.

2

In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats.

Potschka H, Löscher W. Potschka H, et al. Among authors: loscher w. Epilepsia. 2001 Oct;42(10):1231-40. doi: 10.1046/j.1528-1157.2001.01901.x. Epilepsia. 2001. PMID: 11737157 Free article.

3

Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity.

Potschka H, Fedrowitz M, Löscher W. Potschka H, et al. Among authors: loscher w. J Pharmacol Exp Ther. 2003 Jul;306(1):124-31. doi: 10.1124/jpet.103.049858. Epub 2003 Mar 27. J Pharmacol Exp Ther. 2003. PMID: 12663688 Free article.

4

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family.

Löscher W, Potschka H. Löscher W, et al. NeuroRx. 2005 Jan;2(1):86-98. doi: 10.1602/neurorx.2.1.86. NeuroRx. 2005. PMID: 15717060 Free PMC article. Review.

5

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.

Löscher W, Potschka H. Löscher W, et al. Prog Neurobiol. 2005 May;76(1):22-76. doi: 10.1016/j.pneurobio.2005.04.006. Prog Neurobiol. 2005. PMID: 16011870 Review.

6

Exposure to antiepileptic drugs does not alter the functionality of P-glycoprotein in brain capillary endothelial and kidney cell lines.

Ambroziak K, Kuteykin-Teplyakov K, Luna-Tórtos C, Al-Falah M, Fedrowitz M, Löscher W. Ambroziak K, et al. Among authors: loscher w. Eur J Pharmacol. 2010 Feb 25;628(1-3):57-66. doi: 10.1016/j.ejphar.2009.11.051. Epub 2009 Dec 1. Eur J Pharmacol. 2010. PMID: 19958760

7

Do ATP-binding cassette transporters cause pharmacoresistance in epilepsy? Problems and approaches in determining which antiepileptic drugs are affected.

Löscher W, Luna-Tortós C, Römermann K, Fedrowitz M. Löscher W, et al. Curr Pharm Des. 2011;17(26):2808-28. doi: 10.2174/138161211797440212. Curr Pharm Des. 2011. PMID: 21827408 Review.

8

The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study.

Mairinger S, Bankstahl JP, Kuntner C, Römermann K, Bankstahl M, Wanek T, Stanek J, Löscher W, Müller M, Erker T, Langer O. Mairinger S, et al. Among authors: loscher w. Epilepsy Res. 2012 Jun;100(1-2):93-103. doi: 10.1016/j.eplepsyres.2012.01.012. Epub 2012 Feb 17. Epilepsy Res. 2012. PMID: 22342565 Free PMC article.

9

Tariquidar and elacridar are dose-dependently transported by P-glycoprotein and Bcrp at the blood-brain barrier: a small-animal positron emission tomography and in vitro study.

Bankstahl JP, Bankstahl M, Römermann K, Wanek T, Stanek J, Windhorst AD, Fedrowitz M, Erker T, Müller M, Löscher W, Langer O, Kuntner C. Bankstahl JP, et al. Among authors: loscher w. Drug Metab Dispos. 2013 Apr;41(4):754-62. doi: 10.1124/dmd.112.049148. Epub 2013 Jan 10. Drug Metab Dispos. 2013. PMID: 23305710

10

(R)-[(11)C]verapamil is selectively transported by murine and human P-glycoprotein at the blood-brain barrier, and not by MRP1 and BCRP.

Römermann K, Wanek T, Bankstahl M, Bankstahl JP, Fedrowitz M, Müller M, Löscher W, Kuntner C, Langer O. Römermann K, et al. Among authors: loscher w. Nucl Med Biol. 2013 Oct;40(7):873-8. doi: 10.1016/j.nucmedbio.2013.05.012. Epub 2013 Jul 8. Nucl Med Biol. 2013. PMID: 23845421 Free PMC article.

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