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ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo.
Schulz-Kuhnt A, Rühle K, Javidmehr A, Döbrönti M, Biwank J, Knittel S, Neidlinger P, Leupold J, Liu LJ, Dedden M, Taudte RV, Gessner A, Fromm MF, Mielenz D, Kreiss L, Waldner MJ, Schürmann S, Friedrich O, Dietel B, López-Posadas R, Plattner C; TRR241 IBDome Consortium; Zundler S, Becker C, Atreya R, Neurath MF, Atreya I. Schulz-Kuhnt A, et al. Among authors: lopez posadas r. Gut. 2024 Mar 7;73(4):601-612. doi: 10.1136/gutjnl-2023-330543. Gut. 2024. PMID: 38176897
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation.
Martínez-Sánchez LDC, Ngo PA, Pradhan R, Becker LS, Boehringer D, Soteriou D, Kubankova M, Schweitzer C, Koch T, Thonn V, Erkert L, Stolzer I, Günther C, Becker C, Weigmann B, Klewer M, Daniel C, Amann K, Tenzer S, Atreya R, Bergo M, Brakebusch C, Watson AJM, Guck J, Fabry B, Atreya I, Neurath MF, López-Posadas R. Martínez-Sánchez LDC, et al. Among authors: lopez posadas r. Gut. 2023 Feb;72(2):275-294. doi: 10.1136/gutjnl-2021-325520. Epub 2022 Mar 3. Gut. 2023. PMID: 35241625 Free PMC article.
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells.
Ullrich KA, Derdau J, Baltes C, Battistella A, Rosso G, Uderhardt S, Schulze LL, Liu LJ, Dedden M, Spocinska M, Kainka L, Kubánková M, Müller TM, Schmidt NM, Becker E, Ben Brahim O, Atreya I, Finotto S, Prots I, Wirtz S, Weigmann B, López-Posadas R, Atreya R, Ekici AB, Lautenschläger F, Guck J, Neurath MF, Zundler S. Ullrich KA, et al. Among authors: lopez posadas r. Gut. 2023 Nov;72(11):2081-2094. doi: 10.1136/gutjnl-2023-329818. Epub 2023 Aug 4. Gut. 2023. PMID: 37541770 Free PMC article.
Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
López-Posadas R, Fastancz P, Martínez-Sánchez LDC, Panteleev-Ivlev J, Thonn V, Kisseleva T, Becker LS, Schulz-Kuhnt A, Zundler S, Wirtz S, Atreya R, Carlé B, Friedrich O, Schürmann S, Waldner MJ, Neufert C, Brakebusch CH, Bergö MO, Neurath MF, Atreya I. López-Posadas R, et al. Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11. Gastroenterology. 2019. PMID: 31302143 Free article.
ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.
Schulz-Kuhnt A, Greif V, Hildner K, Knipfer L, Döbrönti M, Zirlik S, Fuchs F, Atreya R, Zundler S, López-Posadas R, Neufert C, Ramming A, Kiefer A, Grüneboom A, Strasser E, Wirtz S, Neurath MF, Atreya I. Schulz-Kuhnt A, et al. Front Immunol. 2020 May 7;11:691. doi: 10.3389/fimmu.2020.00691. eCollection 2020. Front Immunol. 2020. PMID: 32457736 Free PMC article.
39 results