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Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab.
Cañas A, López-Sánchez LM, Peñarando J, Valverde A, Conde F, Hernández V, Fuentes E, López-Pedrera C, de la Haba-Rodríguez JR, Aranda E, Rodríguez-Ariza A. Cañas A, et al. Biochim Biophys Acta. 2016 Apr;1862(4):601-610. doi: 10.1016/j.bbadis.2016.02.005. Epub 2016 Feb 6. Biochim Biophys Acta. 2016. PMID: 26854735 Free article.
AEE788 is a vascular endothelial growth factor receptor tyrosine kinase inhibitor with antiproliferative and proapoptotic effects in acute myeloid leukemia.
Barbarroja N, Torres LA, Rodriguez-Ariza A, Valverde-Estepa A, Lopez-Sanchez LM, Ruiz-Limon P, Perez-Sanchez C, Carretero RM, Velasco F, López-Pedrera C. Barbarroja N, et al. Exp Hematol. 2010 Aug;38(8):641-52. doi: 10.1016/j.exphem.2010.03.017. Epub 2010 Apr 7. Exp Hematol. 2010. PMID: 20380868 Free article.
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