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Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.
Ho YH, Del Toro R, Rivera-Torres J, Rak J, Korn C, García-García A, Macías D, González-Gómez C, Del Monte A, Wittner M, Waller AK, Foster HR, López-Otín C, Johnson RS, Nerlov C, Ghevaert C, Vainchenker W, Louache F, Andrés V, Méndez-Ferrer S. Ho YH, et al. Cell Stem Cell. 2019 Sep 5;25(3):407-418.e6. doi: 10.1016/j.stem.2019.06.007. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303548 Free PMC article.
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice.
Espada J, Varela I, Flores I, Ugalde AP, Cadiñanos J, Pendás AM, Stewart CL, Tryggvason K, Blasco MA, Freije JM, López-Otín C. Espada J, et al. J Cell Biol. 2008 Apr 7;181(1):27-35. doi: 10.1083/jcb.200801096. Epub 2008 Mar 31. J Cell Biol. 2008. PMID: 18378773 Free PMC article.
Autophagy and aging: lessons from progeria models.
Mariño G, Fernández AF, López-Otín C. Mariño G, et al. Adv Exp Med Biol. 2010;694:61-8. doi: 10.1007/978-1-4419-7002-2_6. Adv Exp Med Biol. 2010. PMID: 20886757 Review.
Splicing-directed therapy in a new mouse model of human accelerated aging.
Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, De Sandre-Giovannoli A, Freije JM, Lévy N, López-Otín C. Osorio FG, et al. Sci Transl Med. 2011 Oct 26;3(106):106ra107. doi: 10.1126/scitranslmed.3002847. Sci Transl Med. 2011. PMID: 22030750
Reprogramming aging and progeria.
Freije JM, López-Otín C. Freije JM, et al. Curr Opin Cell Biol. 2012 Dec;24(6):757-64. doi: 10.1016/j.ceb.2012.08.009. Epub 2012 Sep 6. Curr Opin Cell Biol. 2012. PMID: 22959961 Review.
NF-kB in premature aging.
Osorio FG, López-Otín C, Freije JM. Osorio FG, et al. Aging (Albany NY). 2012 Nov;4(11):726-7. doi: 10.18632/aging.100502. Aging (Albany NY). 2012. PMID: 23211391 Free PMC article. Review. No abstract available.
The hallmarks of aging.
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. López-Otín C, et al. Cell. 2013 Jun 6;153(6):1194-217. doi: 10.1016/j.cell.2013.05.039. Cell. 2013. PMID: 23746838 Free PMC article. Review.
539 results