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Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery.
Ivanova A, Badertscher L, O'Driscoll G, Bergman J, Gordon E, Gunnarsson A, Johansson C, Munson MJ, Spinelli C, Torstensson S, Vilén L, Voirel A, Wiseman J, Rak J, Dekker N, Lázaro-Ibáñez E. Ivanova A, et al. Among authors: lazaro ibanez e. Adv Sci (Weinh). 2023 Dec;10(34):e2304389. doi: 10.1002/advs.202304389. Epub 2023 Oct 22. Adv Sci (Weinh). 2023. PMID: 37867228 Free PMC article.
Quantification of protein cargo loading into engineered extracellular vesicles at single-vesicle and single-molecule resolution.
Silva AM, Lázaro-Ibáñez E, Gunnarsson A, Dhande A, Daaboul G, Peacock B, Osteikoetxea X, Salmond N, Friis KP, Shatnyeva O, Dekker N. Silva AM, et al. Among authors: lazaro ibanez e. J Extracell Vesicles. 2021 Aug;10(10):e12130. doi: 10.1002/jev2.12130. Epub 2021 Aug 2. J Extracell Vesicles. 2021. PMID: 34377376 Free PMC article.
Engineered Cas9 extracellular vesicles as a novel gene editing tool.
Osteikoetxea X, Silva A, Lázaro-Ibáñez E, Salmond N, Shatnyeva O, Stein J, Schick J, Wren S, Lindgren J, Firth M, Madsen A, Mayr LM, Overman R, Davies R, Dekker N. Osteikoetxea X, et al. Among authors: lazaro ibanez e. J Extracell Vesicles. 2022 May;11(5):e12225. doi: 10.1002/jev2.12225. J Extracell Vesicles. 2022. PMID: 35585651 Free PMC article.
Extracellular vesicles induce minimal hepatotoxicity and immunogenicity.
Saleh AF , Lázaro-Ibáñez E , Forsgard MA , Shatnyeva O , Osteikoetxea X , Karlsson F , Heath N , Ingelsten M , Rose J , Harris J , Mairesse M , Bates SM , Clausen M , Etal D , Leonard E , Fellows MD , Dekker N , Edmunds N . Saleh AF , et al. Nanoscale. 2019 Apr 4;11(14):6990-7001. doi: 10.1039/c8nr08720b. Nanoscale. 2019. PMID: 30916672
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönit… See abstract for full author list ➔ Théry C, et al. J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. eCollection 2018. J Extracell Vesicles. 2018. PMID: 30637094 Free PMC article.
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.
Arasu UT, Deen AJ, Pasonen-Seppänen S, Heikkinen S, Lalowski M, Kärnä R, Härkönen K, Mäkinen P, Lázaro-Ibáñez E, Siljander PR, Oikari S, Levonen AL, Rilla K. Arasu UT, et al. Cell Mol Life Sci. 2020 Oct;77(20):4093-4115. doi: 10.1007/s00018-019-03399-5. Epub 2019 Dec 9. Cell Mol Life Sci. 2020. PMID: 31820036 Free PMC article.
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