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Synergistic antitumour effects of rapamycin and oncolytic reovirus.
Comins C, Simpson GR, Rogers W, Relph K, Harrington K, Melcher A, Roulstone V, Kyula J, Pandha H. Comins C, et al. Among authors: kyula j. Cancer Gene Ther. 2018 Jun;25(5-6):148-160. doi: 10.1038/s41417-018-0011-8. Epub 2018 May 3. Cancer Gene Ther. 2018. PMID: 29720674
Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy.
Roulstone V, Twigger K, Zaidi S, Pencavel T, Kyula JN, White C, McLaughlin M, Seth R, Karapanagiotou EM, Mansfield D, Coffey M, Nuovo G, Vile RG, Pandha HS, Melcher AA, Harrington KJ. Roulstone V, et al. Among authors: kyula jn. Gene Ther. 2013 May;20(5):521-8. doi: 10.1038/gt.2012.68. Epub 2012 Aug 16. Gene Ther. 2013. PMID: 22895509 Free PMC article.
Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.
Twigger K, Roulstone V, Kyula J, Karapanagiotou EM, Syrigos KN, Morgan R, White C, Bhide S, Nuovo G, Coffey M, Thompson B, Jebar A, Errington F, Melcher AA, Vile RG, Pandha HS, Harrington KJ. Twigger K, et al. Among authors: kyula j. BMC Cancer. 2012 Aug 24;12:368. doi: 10.1186/1471-2407-12-368. BMC Cancer. 2012. PMID: 22920673 Free PMC article.
BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress.
Roulstone V, Pedersen M, Kyula J, Mansfield D, Khan AA, McEntee G, Wilkinson M, Karapanagiotou E, Coffey M, Marais R, Jebar A, Errington-Mais F, Melcher A, Vile R, Pandha H, McLaughlin M, Harrington KJ. Roulstone V, et al. Among authors: kyula j. Mol Ther. 2015 May;23(5):931-942. doi: 10.1038/mt.2015.15. Epub 2015 Jan 26. Mol Ther. 2015. PMID: 25619724 Free PMC article.
The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism.
McLaughlin M, Pedersen M, Roulstone V, Bergerhoff KF, Smith HG, Whittock H, Kyula JN, Dillon MT, Pandha HS, Vile R, Melcher AA, Harrington KJ. McLaughlin M, et al. Among authors: kyula jn. Mol Ther Oncolytics. 2020 Jan 17;16:238-249. doi: 10.1016/j.omto.2020.01.001. eCollection 2020 Mar 27. Mol Ther Oncolytics. 2020. PMID: 32128359 Free PMC article.
Oncolytic Vaccinia virus and radiotherapy in head and neck cancer.
Mansfield D, Pencavel T, Kyula JN, Zaidi S, Roulstone V, Thway K, Karapanagiotou L, Khan AA, McLaughlin M, Touchefeu Y, Seth R, Melcher AA, Vile RG, Pandha HS, Harrington KJ. Mansfield D, et al. Among authors: kyula jn. Oral Oncol. 2013 Feb;49(2):108-18. doi: 10.1016/j.oraloncology.2012.07.019. Epub 2012 Aug 25. Oral Oncol. 2013. PMID: 22925693
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