Kyle DJ - Search Results

1

Pharmacology of a new cyclic nucleotide phosphodiesterase type 4 inhibitor, V11294.

Gale DD, Hofer P, Spina D, Seeds EA, Banner KH, Harrison S, Douglas G, Matsumoto T, Page CP, Wong RH, Jordan S, Smith F, Banik N, Halushka PV, Cavalla D, Rotshteyn Y, Kyle DJ, Burch RM, Chasin M. Gale DD, et al. Among authors: kyle dj. Pulm Pharmacol Ther. 2003;16(2):97-104. doi: 10.1016/S1094-5539(02)00175-X. Pulm Pharmacol Ther. 2003. PMID: 12670778 Review.

2

DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted mu opioid agonist with antihyperalgesic activity: I. In vitro pharmacological characterization and pharmacokinetic properties.

Valenzano KJ, Miller W, Chen Z, Shan S, Crumley G, Victory SF, Davies E, Huang JC, Allie N, Nolan SJ, Rotshteyn Y, Kyle DJ, Broglé K. Valenzano KJ, et al. Among authors: kyle dj. J Pharmacol Exp Ther. 2004 Aug;310(2):783-92. doi: 10.1124/jpet.103.063313. Epub 2004 Mar 30. J Pharmacol Exp Ther. 2004. PMID: 15054115

3

8-Substituted analogues of 3-(3-cyclopentyloxy-4-methoxy-benzyl)-8-isopropyl-adenine: highly potent and selective PDE4 inhibitors.

Whitehead JW, Lee GP, Gharagozloo P, Hofer P, Gehrig A, Wintergerst P, Smyth D, McCoull W, Hachicha M, Patel A, Kyle DJ. Whitehead JW, et al. Among authors: kyle dj. J Med Chem. 2005 Feb 24;48(4):1237-43. doi: 10.1021/jm030603w. J Med Chem. 2005. PMID: 15715490

4

D-Arg[Hyp3-Thi5-D-Tic7-Tic8]-bradykinin, a potent antagonist of smooth muscle BK2 receptors and BK3 receptors.

Farmer SG, Burch RM, Kyle DJ, Martin JA, Meeker SN, Togo J. Farmer SG, et al. Among authors: kyle dj. Br J Pharmacol. 1991 Apr;102(4):785-7. doi: 10.1111/j.1476-5381.1991.tb12251.x. Br J Pharmacol. 1991. PMID: 1649657 Free PMC article.

5

Mass receptor screening for new drugs.

Burch RM, Kyle DJ. Burch RM, et al. Among authors: kyle dj. Pharm Res. 1991 Feb;8(2):141-7. doi: 10.1023/a:1015819431855. Pharm Res. 1991. PMID: 1850826 Review.

6

4-(2-pyridyl)piperazine-1-carboxamides: potent vanilloid receptor 1 antagonists.

Sun Q, Tafesse L, Islam K, Zhou X, Victory SF, Zhang C, Hachicha M, Schmid LA, Patel A, Rotshteyn Y, Valenzano KJ, Kyle DJ. Sun Q, et al. Among authors: kyle dj. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3611-6. doi: 10.1016/s0960-894x(03)00759-5. Bioorg Med Chem Lett. 2003. PMID: 14505681

7

Synthesis and evaluation of pyridazinylpiperazines as vanilloid receptor 1 antagonists.

Tafesse L, Sun Q, Schmid L, Valenzano KJ, Rotshteyn Y, Su X, Kyle DJ. Tafesse L, et al. Among authors: kyle dj. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5513-9. doi: 10.1016/j.bmcl.2004.09.010. Bioorg Med Chem Lett. 2004. PMID: 15482915

8

Recent developments in the understanding of bradykinin receptors.

Burch RM, Kyle DJ. Burch RM, et al. Among authors: kyle dj. Life Sci. 1992;50(12):829-38. doi: 10.1016/0024-3205(92)90201-y. Life Sci. 1992. PMID: 1372060 Review.

9

Design and conformational analysis of several highly potent bradykinin receptor antagonists.

Kyle DJ, Martin JA, Farmer SG, Burch RM. Kyle DJ, et al. J Med Chem. 1991 Mar;34(3):1230-3. doi: 10.1021/jm00107a052. J Med Chem. 1991. PMID: 1848297 No abstract available.

10

Probing the bradykinin receptor: mapping the geometric topography using ethers of hydroxyproline in novel peptides.

Kyle DJ, Martin JA, Burch RM, Carter JP, Lu SF, Meeker S, Prosser JC, Sullivan JP, Togo J, Noronha-Blob L, et al. Kyle DJ, et al. J Med Chem. 1991 Aug;34(8):2649-53. doi: 10.1021/jm00112a047. J Med Chem. 1991. PMID: 1652027 No abstract available.

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