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SETD3 protein is the actin-specific histidine N-methyltransferase.
Kwiatkowski S, Seliga AK, Vertommen D, Terreri M, Ishikawa T, Grabowska I, Tiebe M, Teleman AA, Jagielski AK, Veiga-da-Cunha M, Drozak J. Kwiatkowski S, et al. Elife. 2018 Dec 11;7:e37921. doi: 10.7554/eLife.37921. Elife. 2018. PMID: 30526847 Free PMC article.
Structural insights into SETD3-mediated histidine methylation on β-actin.
Guo Q, Liao S, Kwiatkowski S, Tomaka W, Yu H, Wu G, Tu X, Min J, Drozak J, Xu C. Guo Q, et al. Among authors: kwiatkowski s. Elife. 2019 Feb 20;8:e43676. doi: 10.7554/eLife.43676. Elife. 2019. PMID: 30785395 Free PMC article.
Previously, we identified SETD3 as the actin-specific methyltransferase that methylates the N3 of His73 on beta-actin (Kwiatkowski et al., 2018). Here, we present two structures of S-adenosyl-L-homocysteine-bound SETD3 in complex with either an unmodified beta-actin …
Previously, we identified SETD3 as the actin-specific methyltransferase that methylates the N3 of His73 on beta-actin (Kwiatkowski et …
Protein Histidine Methylation.
Kwiatkowski S, Drozak J. Kwiatkowski S, et al. Curr Protein Pept Sci. 2020;21(7):675-689. doi: 10.2174/1389203721666200318161330. Curr Protein Pept Sci. 2020. PMID: 32188384 Review.
β-Actin Peptide-Based Inhibitors of Histidine Methyltransferase SETD3.
Hintzen JCJ, Moesgaard L, Kwiatkowski S, Drozak J, Kongsted J, Mecinović J. Hintzen JCJ, et al. Among authors: kwiatkowski s. ChemMedChem. 2021 Sep 6;16(17):2695-2702. doi: 10.1002/cmdc.202100296. Epub 2021 Jun 22. ChemMedChem. 2021. PMID: 34032009
Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β-alanine transamination.
Blancquaert L, Baba SP, Kwiatkowski S, Stautemas J, Stegen S, Barbaresi S, Chung W, Boakye AA, Hoetker JD, Bhatnagar A, Delanghe J, Vanheel B, Veiga-da-Cunha M, Derave W, Everaert I. Blancquaert L, et al. Among authors: kwiatkowski s. J Physiol. 2016 Sep 1;594(17):4849-63. doi: 10.1113/JP272050. Epub 2016 Jun 2. J Physiol. 2016. PMID: 27062388 Free PMC article.
Loss of function TRPV6 variants are associated with chronic pancreatitis in nonalcoholic early-onset Polish and German patients.
Oracz G, Zaród M, Ewers M, Laumen H, Gambin T, Kamiński P, Grabowska I, Drożak A, Kwiatkowski S, Wertheim-Tysarowska K, Kołodziejczyk E, Domaszewicz A, Dorożko B, Kosińska J, Głuszek S, Kozieł D, Płoski R, Rosendahl J, Witt H, Drożak J, Rygiel AM. Oracz G, et al. Among authors: kwiatkowski s. Pancreatology. 2021 Dec;21(8):1434-1442. doi: 10.1016/j.pan.2021.09.005. Epub 2021 Sep 10. Pancreatology. 2021. PMID: 34538581
277 results