Structural insights into SETD3-mediated histidine methylation on β-actin.
Guo Q, Liao S, Kwiatkowski S, Tomaka W, Yu H, Wu G, Tu X, Min J, Drozak J, Xu C.
Guo Q, et al. Among authors: kwiatkowski s.
Elife. 2019 Feb 20;8:e43676. doi: 10.7554/eLife.43676.
Elife. 2019.
PMID: 30785395
Free PMC article.
Previously, we identified SETD3 as the actin-specific methyltransferase that methylates the N3 of His73 on beta-actin (Kwiatkowski et al., 2018). Here, we present two structures of S-adenosyl-L-homocysteine-bound SETD3 in complex with either an unmodified beta-actin …
Previously, we identified SETD3 as the actin-specific methyltransferase that methylates the N3 of His73 on beta-actin (Kwiatkowski et …