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Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA).
Ratni H, Ebeling M, Baird J, Bendels S, Bylund J, Chen KS, Denk N, Feng Z, Green L, Guerard M, Jablonski P, Jacobsen B, Khwaja O, Kletzl H, Ko CP, Kustermann S, Marquet A, Metzger F, Mueller B, Naryshkin NA, Paushkin SV, Pinard E, Poirier A, Reutlinger M, Weetall M, Zeller A, Zhao X, Mueller L. Ratni H, et al. Among authors: kustermann s. J Med Chem. 2018 Aug 9;61(15):6501-6517. doi: 10.1021/acs.jmedchem.8b00741. Epub 2018 Jul 25. J Med Chem. 2018. PMID: 30044619
Human Retinal Microvasculature-on-a-Chip for Drug Discovery.
Ragelle H, Dernick K, Khemais S, Keppler C, Cousin L, Farouz Y, Louche C, Fauser S, Kustermann S, Tibbitt MW, Westenskow PD. Ragelle H, et al. Among authors: kustermann s. Adv Healthc Mater. 2020 Nov;9(21):e2001531. doi: 10.1002/adhm.202001531. Epub 2020 Sep 24. Adv Healthc Mater. 2020. PMID: 32975047
Organ-On-A-Chip Technologies for Advanced Blood-Retinal Barrier Models.
Ragelle H, Goncalves A, Kustermann S, Antonetti DA, Jayagopal A. Ragelle H, et al. Among authors: kustermann s. J Ocul Pharmacol Ther. 2020 Jan/Feb;36(1):30-41. doi: 10.1089/jop.2019.0017. Epub 2019 May 29. J Ocul Pharmacol Ther. 2020. PMID: 31140899 Free PMC article. Review.
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Krebs A, et al. Among authors: kustermann s. ALTEX. 2019;36(4):682-699. doi: 10.14573/altex.1909271. ALTEX. 2019. PMID: 31658359 Free article.
Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M. Krebs A, et al. Among authors: kustermann s. ALTEX. 2020;37(1):164. doi: 10.14573/altex.1909271e. ALTEX. 2020. PMID: 31960940 Free article.
In vitro teratogenicity testing using a 3D, embryo-like gastruloid system.
Mantziou V, Baillie-Benson P, Jaklin M, Kustermann S, Arias AM, Moris N. Mantziou V, et al. Among authors: kustermann s. Reprod Toxicol. 2021 Oct;105:72-90. doi: 10.1016/j.reprotox.2021.08.003. Epub 2021 Aug 20. Reprod Toxicol. 2021. PMID: 34425190 Free PMC article.
30 results