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Page 1
Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model.
Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuch T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi S, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: kushiyama a. J Biol Chem. 2012 Dec 28;287(53):44526-35. doi: 10.1074/jbc.M112.397133. Epub 2012 Oct 29. J Biol Chem. 2012. PMID: 23112047 Free PMC article.
Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity.
Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Horike N, Yoneda M, Ohno H, Tsuchiya Y, Kamata H, Tahara H, Isobe T, Nishimura F, Katagiri H, Oka Y, Fukushima T, Takahashi SI, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: kushiyama a. J Biol Chem. 2010 Oct 22;285(43):33018-33027. doi: 10.1074/jbc.M110.137836. Epub 2010 Jul 30. J Biol Chem. 2010. PMID: 20675384 Free PMC article.
Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow.
Shojima N, Ogihara T, Inukai K, Fujishiro M, Sakoda H, Kushiyama A, Katagiri H, Anai M, Ono H, Fukushima Y, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Shojima N, et al. Among authors: kushiyama a. Diabetologia. 2005 May;48(5):984-92. doi: 10.1007/s00125-005-1735-1. Epub 2005 Apr 15. Diabetologia. 2005. PMID: 15834545
Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.
Sakoda H, Fujishiro M, Fujio J, Shojima N, Ogihara T, Kushiyama A, Fukushima Y, Anai M, Ono H, Kikuchi M, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Sakoda H, et al. Among authors: kushiyama a. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E474-81. doi: 10.1152/ajpendo.00003.2005. Epub 2005 May 10. Am J Physiol Endocrinol Metab. 2005. PMID: 15886229 Free article.
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.
Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T. Horike N, et al. Among authors: kushiyama a. J Biol Chem. 2008 Dec 5;283(49):33902-10. doi: 10.1074/jbc.M802537200. Epub 2008 Sep 17. J Biol Chem. 2008. PMID: 18801732 Free PMC article.
The inflammation-lipocalin 2 axis may contribute to the development of chronic kidney disease.
Hashikata A, Yamashita A, Suzuki S, Nagayasu S, Shinjo T, Taniguchi A, Fukushima M, Nakai Y, Nin K, Watanabe N, Asano T, Abiko Y, Kushiyama A, Nagasaka S, Nishimura F. Hashikata A, et al. Among authors: kushiyama a. Nephrol Dial Transplant. 2014 Mar;29(3):611-8. doi: 10.1093/ndt/gft449. Epub 2013 Nov 13. Nephrol Dial Transplant. 2014. PMID: 24235082
Regulation of gut-derived resistin-like molecule beta expression by nutrients.
Fujio J, Kushiyama A, Sakoda H, Fujishiro M, Ogihara T, Fukushima Y, Anai M, Horike N, Kamata H, Uchijima Y, Kurihara H, Asano T. Fujio J, et al. Among authors: kushiyama a. Diabetes Res Clin Pract. 2008 Jan;79(1):2-10. doi: 10.1016/j.diabres.2007.04.015. Epub 2007 Oct 23. Diabetes Res Clin Pract. 2008. PMID: 17936398
117 results