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Deep thermal profiling for detection of functional proteoform groups.
Kurzawa N, Leo IR, Stahl M, Kunold E, Becher I, Audrey A, Mermelekas G, Huber W, Mateus A, Savitski MM, Jafari R. Kurzawa N, et al. Nat Chem Biol. 2023 Aug;19(8):962-971. doi: 10.1038/s41589-023-01284-8. Epub 2023 Mar 20. Nat Chem Biol. 2023. PMID: 36941476 Free PMC article.
Systematic discovery of biomolecular condensate-specific protein phosphorylation.
Sridharan S, Hernandez-Armendariz A, Kurzawa N, Potel CM, Memon D, Beltrao P, Bantscheff M, Huber W, Cuylen-Haering S, Savitski MM. Sridharan S, et al. Among authors: kurzawa n. Nat Chem Biol. 2022 Oct;18(10):1104-1114. doi: 10.1038/s41589-022-01062-y. Epub 2022 Jul 21. Nat Chem Biol. 2022. PMID: 35864335 Free PMC article.
Drug Target Identification in Tissues by Thermal Proteome Profiling.
Mateus A, Kurzawa N, Perrin J, Bergamini G, Savitski MM. Mateus A, et al. Among authors: kurzawa n. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:465-482. doi: 10.1146/annurev-pharmtox-052120-013205. Epub 2021 Sep 9. Annu Rev Pharmacol Toxicol. 2022. PMID: 34499524 Review.
Impact of phosphorylation on thermal stability of proteins.
Potel CM, Kurzawa N, Becher I, Typas A, Mateus A, Savitski MM. Potel CM, et al. Among authors: kurzawa n. Nat Methods. 2021 Jul;18(7):757-759. doi: 10.1038/s41592-021-01177-5. Epub 2021 Jun 17. Nat Methods. 2021. PMID: 34140700 No abstract available.
SARS-CoV-2 infection remodels the host protein thermal stability landscape.
Selkrig J, Stanifer M, Mateus A, Mitosch K, Barrio-Hernandez I, Rettel M, Kim H, Voogdt CGP, Walch P, Kee C, Kurzawa N, Stein F, Potel C, Jarzab A, Kuster B, Bartenschlager R, Boulant S, Beltrao P, Typas A, Savitski MM. Selkrig J, et al. Among authors: kurzawa n. Mol Syst Biol. 2021 Feb;17(2):e10188. doi: 10.15252/msb.202010188. Mol Syst Biol. 2021. PMID: 33590968 Free PMC article.
ShinyButchR: Interactive NMF-based decomposition workflow of genome-scale datasets.
Quintero A, Hübschmann D, Kurzawa N, Steinhauser S, Rentzsch P, Krämer S, Andresen C, Park J, Eils R, Schlesner M, Herrmann C. Quintero A, et al. Among authors: kurzawa n. Biol Methods Protoc. 2020 Oct 29;5(1):bpaa022. doi: 10.1093/biomethods/bpaa022. eCollection 2020. Biol Methods Protoc. 2020. PMID: 33376806 Free PMC article.
The functional proteome landscape of Escherichia coli.
Mateus A, Hevler J, Bobonis J, Kurzawa N, Shah M, Mitosch K, Goemans CV, Helm D, Stein F, Typas A, Savitski MM. Mateus A, et al. Among authors: kurzawa n. Nature. 2020 Dec;588(7838):473-478. doi: 10.1038/s41586-020-3002-5. Epub 2020 Dec 9. Nature. 2020. PMID: 33299184 Free PMC article.
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