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Distinct and targetable role of calcium-sensing receptor in leukaemia.
Pereira RS, Kumar R, Cais A, Paulini L, Kahler A, Bravo J, Minciacchi VR, Krack T, Kowarz E, Zanetti C, Godavarthy PS, Hoeller F, Llavona P, Stark T, Tascher G, Nowak D, Meduri E, Huntly BJP, Münch C, Pampaloni F, Marschalek R, Krause DS. Pereira RS, et al. Among authors: kumar r. Nat Commun. 2023 Oct 6;14(1):6242. doi: 10.1038/s41467-023-41770-0. Nat Commun. 2023. PMID: 37802982 Free PMC article.
Vitamin K antagonism impairs the bone marrow microenvironment and hematopoiesis.
Verma D, Kumar R, Pereira RS, Karantanou C, Zanetti C, Minciacchi VR, Fulzele K, Kunz K, Hoelper S, Zia-Chahabi S, Jabagi MJ, Emmerich J, Dray-Spira R, Kuhlee F, Hackmann K, Schroeck E, Wenzel P, Müller S, Filmann N, Fontenay M, Pajevic PD, Krause DS. Verma D, et al. Among authors: kumar r. Blood. 2019 Jul 18;134(3):227-238. doi: 10.1182/blood.2018874214. Epub 2019 Apr 19. Blood. 2019. PMID: 31003999 Free PMC article.
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis.
Godavarthy PS, Kumar R, Herkt SC, Pereira RS, Hayduk N, Weissenberger ES, Aggoune D, Manavski Y, Lucas T, Pan KT, Voutsinas JM, Wu Q, Müller MC, Saussele S, Oellerich T, Oehler VG, Lausen J, Krause DS. Godavarthy PS, et al. Among authors: kumar r. Haematologica. 2020 Jan;105(1):136-147. doi: 10.3324/haematol.2018.212365. Epub 2019 Apr 24. Haematologica. 2020. PMID: 31018977 Free PMC article.
Bone marrow niche-derived extracellular matrix-degrading enzymes influence the progression of B-cell acute lymphoblastic leukemia.
Verma D, Zanetti C, Godavarthy PS, Kumar R, Minciacchi VR, Pfeiffer J, Metzler M, Lefort S, Maguer-Satta V, Nicolini FE, Burroni B, Fontenay M, Krause DS. Verma D, et al. Among authors: kumar r. Leukemia. 2020 Jun;34(6):1540-1552. doi: 10.1038/s41375-019-0674-7. Epub 2020 Jan 9. Leukemia. 2020. PMID: 31919471 Free PMC article.
Specific, targetable interactions with the microenvironment influence imatinib-resistant chronic myeloid leukemia.
Kumar R, Pereira RS, Zanetti C, Minciacchi VR, Merten M, Meister M, Niemann J, Dietz MS, Rüssel N, Schnütgen F, Tamai M, Akahane K, Inukai T, Oellerich T, Kvasnicka HM, Pfeifer H, Nicolini FE, Heilemann M, Van Etten RA, Krause DS. Kumar R, et al. Leukemia. 2020 Aug;34(8):2087-2101. doi: 10.1038/s41375-020-0866-1. Epub 2020 May 21. Leukemia. 2020. PMID: 32439895 Free PMC article.
The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13.
Zanetti C, Kumar R, Ender J, Godavarthy PS, Hartmann M, Hey J, Breuer K, Weissenberger ES, Minciacchi VR, Karantanou C, Gu Z, Roberts KG, Metzler M, Stock W, Mullighan CG, Bloomfield CD, Filmann N, Bankov K, Hartmann S, Hasserjian RP, Cousins AF, Halsey C, Plass C, Lipka DB, Krause DS. Zanetti C, et al. Among authors: kumar r. Blood. 2021 Nov 11;138(19):1870-1884. doi: 10.1182/blood.2021011557. Blood. 2021. PMID: 34424946 Free PMC article.
The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia.
Kumar R, Pereira RS, Niemann J, Azimpour AI, Zanetti C, Karantanou C, Minka W, Minciacchi VR, Kowarz E, Meister M, Godavarthy PS, Maguer-Satta V, Lefort S, Wiercinska E, Bonig H, Marschalek R, Krause DS. Kumar R, et al. Blood Adv. 2022 Jun 28;6(12):3611-3624. doi: 10.1182/bloodadvances.2021005992. Blood Adv. 2022. PMID: 35298613 Free PMC article.
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