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Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis.
Stepien DM, Hwang C, Marini S, Pagani CA, Sorkin M, Visser ND, Huber AK, Edwards NJ, Loder SJ, Vasquez K, Aguilar CA, Kumar R, Mascharak S, Longaker MT, Li J, Levi B. Stepien DM, et al. Among authors: kumar r. J Immunol. 2020 Apr 15;204(8):2203-2215. doi: 10.4049/jimmunol.1900814. Epub 2020 Mar 11. J Immunol. 2020. PMID: 32161098 Free PMC article.
Macrophage TGF-β signaling is critical for wound healing with heterotopic ossification after trauma.
Patel NK, Nunez JH, Sorkin M, Marini S, Pagani CA, Strong AL, Hwang CD, Li S, Padmanabhan KR, Kumar R, Bancroft AC, Greenstein JA, Nelson R, Rasheed HA, Livingston N, Vasquez K, Huber AK, Levi B. Patel NK, et al. Among authors: kumar r. JCI Insight. 2022 Oct 24;7(20):e144925. doi: 10.1172/jci.insight.144925. JCI Insight. 2022. PMID: 36099022 Free PMC article.
Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle.
Castonguay R, Lachey J, Wallner S, Strand J, Liharska K, Watanabe AE, Cannell M, Davies MV, Sako D, Troy ME, Krishnan L, Mulivor AW, Li H, Keates S, Alexander MJ, Pearsall RS, Kumar R. Castonguay R, et al. Among authors: kumar r. J Pharmacol Exp Ther. 2019 Mar;368(3):435-445. doi: 10.1124/jpet.118.252304. Epub 2018 Dec 18. J Pharmacol Exp Ther. 2019. PMID: 30563942
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.
Pearsall RS, Davies MV, Cannell M, Li J, Widrick J, Mulivor AW, Wallner S, Troy ME, Spaits M, Liharska K, Sako D, Castonguay R, Keates S, Grinberg AV, Suragani RNVS, Kumar R. Pearsall RS, et al. Among authors: kumar r. Sci Rep. 2019 Aug 6;9(1):11392. doi: 10.1038/s41598-019-47818-w. Sci Rep. 2019. PMID: 31388039 Free PMC article.
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