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Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: kumar n. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
Small molecule inhibitors of bacterial transcription complex formation.
Wenholz DS, Zeng M, Ma C, Mielczarek M, Yang X, Bhadbhade M, Black DSC, Lewis PJ, Griffith R, Kumar N. Wenholz DS, et al. Among authors: kumar n. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4302-4308. doi: 10.1016/j.bmcl.2017.08.036. Epub 2017 Aug 19. Bioorg Med Chem Lett. 2017. PMID: 28866270
Glyoxylamide-based self-assembly hydrogels for sustained ciprofloxacin delivery.
Aldilla VR , Martin AD , Nizalapur S , Marjo CE , Rich AM , Ho KKK , Ittner LM , Black DS , Thordarson P , Kumar N . Aldilla VR , et al. Among authors: kumar n. J Mater Chem B. 2018 Oct 14;6(38):6089-6098. doi: 10.1039/c8tb01290c. Epub 2018 Sep 10. J Mater Chem B. 2018. PMID: 32254819
Synthetic Bilayers on Mica from Self-Assembly of Hydrogen-Bonded Triazines.
Yao Y, Aldilla VR, Bhadbhade M, Bhattacharyya S, Gong B, Kumar N, Rich AM, Sando D, Cheong S, Tilley R, Yin S, Marjo CE. Yao Y, et al. Among authors: kumar n. Langmuir. 2020 Nov 10;36(44):13301-13311. doi: 10.1021/acs.langmuir.0c02377. Epub 2020 Oct 27. Langmuir. 2020. PMID: 33108206
Natural Product Rottlerin Derivatives Targeting Quorum Sensing.
Suresh D, Sabir S, Yu TT, Wenholz D, Das T, Black DS, Kumar N. Suresh D, et al. Among authors: kumar n. Molecules. 2021 Jun 19;26(12):3745. doi: 10.3390/molecules26123745. Molecules. 2021. PMID: 34205355 Free PMC article.
Inhibitors of bacterial RNA polymerase transcription complex.
Wenholz DS, Miller M, Dawson C, Bhadbhade M, Black DS, Griffith R, Dinh H, Cain A, Lewis P, Kumar N. Wenholz DS, et al. Among authors: kumar n. Bioorg Chem. 2022 Jan;118:105481. doi: 10.1016/j.bioorg.2021.105481. Epub 2021 Nov 13. Bioorg Chem. 2022. PMID: 34801947
8,798 results