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Modulating mitofusins to control mitochondrial function and signaling.
Nat Commun. 2022 Jul 7;13(1):3775. doi: 10.1038/s41467-022-31324-1.
Nat Commun. 2022.
PMID: 35798717
Free PMC article.
Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors.
Kazi A, Ranjan A, Kumar M V V, Agianian B, Garcia Chavez M, Vudatha V, Wang R, Vangipurapu R, Chen L, Kennedy P, Subramanian K, Quirke JCK, Beato F, Underwood PW, Fleming JB, Trevino J, Hergenrother PJ, Gavathiotis E, Sebti SM.
Kazi A, et al.
Cancer Res Commun. 2023 Dec 28;3(12):2623-2639. doi: 10.1158/2767-9764.CRC-23-0222.
Cancer Res Commun. 2023.
PMID: 38051103
Free PMC article.
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Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis.
Gitego N, Agianian B, Mak OW, Kumar Mv V, Cheng EH, Gavathiotis E.
Gitego N, et al. Among authors: kumar mv v.
Nat Commun. 2023 Dec 16;14(1):8381. doi: 10.1038/s41467-023-44084-3.
Nat Commun. 2023.
PMID: 38104127
Free PMC article.
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Molecular insights into the interaction of Hsp90 with allosteric inhibitors targeting the C-terminal domain.
Kumar Mv V, Ebna Noor R, Davis RE, Zhang Z, Sipavicius E, Keramisanou D, Blagg BSJ, Gelis I.
Kumar Mv V, et al.
Medchemcomm. 2018 Jul 2;9(8):1323-1331. doi: 10.1039/c8md00151k. eCollection 2018 Aug 1.
Medchemcomm. 2018.
PMID: 30151087
Free PMC article.
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1H, 13C, and 15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
Marquevielle J, Kumar MVV, Mergny JL, Salgado GF.
Marquevielle J, et al.
Biomol NMR Assign. 2018 Apr;12(1):123-127. doi: 10.1007/s12104-017-9793-0. Epub 2017 Nov 30.
Biomol NMR Assign. 2018.
PMID: 29189986
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