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432 results

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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy.
Khattar E, Maung KZY, Chew CL, Ghosh A, Mok MMH, Lee P, Zhang J, Chor WHJ, Cildir G, Wang CQ, Mohd-Ismail NK, Chin DWL, Lee SC, Yang H, Shin YJ, Nam DH, Chen L, Kumar AP, Deng LW, Ikawa M, Gunaratne J, Osato M, Tergaonkar V. Khattar E, et al. Among authors: kumar ap. Nat Commun. 2019 Dec 13;10(1):5349. doi: 10.1038/s41467-019-13082-9. Nat Commun. 2019. PMID: 31836706 Free PMC article.
Multifaceted link between cancer and inflammation.
Sethi G, Shanmugam MK, Ramachandran L, Kumar AP, Tergaonkar V. Sethi G, et al. Among authors: kumar ap. Biosci Rep. 2012 Feb;32(1):1-15. doi: 10.1042/BSR20100136. Biosci Rep. 2012. PMID: 21981137 Review.
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.
Rajendran P, Li F, Shanmugam MK, Kannaiyan R, Goh JN, Wong KF, Wang W, Khin E, Tergaonkar V, Kumar AP, Luk JM, Sethi G. Rajendran P, et al. Among authors: kumar ap. Cancer Prev Res (Phila). 2012 Apr;5(4):631-43. doi: 10.1158/1940-6207.CAPR-11-0420. Epub 2012 Feb 27. Cancer Prev Res (Phila). 2012. PMID: 22369852
Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds.
Shanmugam MK, Lee JH, Chai EZ, Kanchi MM, Kar S, Arfuso F, Dharmarajan A, Kumar AP, Ramar PS, Looi CY, Mustafa MR, Tergaonkar V, Bishayee A, Ahn KS, Sethi G. Shanmugam MK, et al. Among authors: kumar ap. Semin Cancer Biol. 2016 Oct;40-41:35-47. doi: 10.1016/j.semcancer.2016.03.005. Epub 2016 Mar 30. Semin Cancer Biol. 2016. PMID: 27038646 Review.
RNA helicase DP103 and TAK1: a new connection in cancer.
Shin EM, Osato M, Kumar AP, Tergaonkar V. Shin EM, et al. Among authors: kumar ap. Mol Cell Oncol. 2015 Jan 26;2(3):e985911. doi: 10.4161/23723556.2014.985911. eCollection 2015 Jul-Sep. Mol Cell Oncol. 2015. PMID: 27308465 Free PMC article. No abstract available.
PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers.
Chen L, Yuan Y, Kar S, Kanchi MM, Arora S, Kim JE, Koh PF, Yousef E, Samy RP, Shanmugam MK, Tan TZ, Shin SW, Arfuso F, Shen HM, Yang H, Goh BC, Park JI, Gaboury L, Lobie PE, Sethi G, Lim LHK, Kumar AP. Chen L, et al. Among authors: kumar ap. Mol Cancer Ther. 2017 Nov;16(11):2528-2542. doi: 10.1158/1535-7163.MCT-16-0739. Epub 2017 Aug 15. Mol Cancer Ther. 2017. PMID: 29021293
The expanding roles of long non-coding RNAs in the regulation of cancer stem cells.
Ma Z, Wang YY, Xin HW, Wang L, Arfuso F, Dharmarajan A, Kumar AP, Wang H, Tang FR, Warrier S, Tergaonkar V, Sethi G. Ma Z, et al. Among authors: kumar ap. Int J Biochem Cell Biol. 2019 Mar;108:17-20. doi: 10.1016/j.biocel.2019.01.003. Epub 2019 Jan 7. Int J Biochem Cell Biol. 2019. PMID: 30630112 Review.
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.
Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saei A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP. Sim WJ, et al. Among authors: kumar ap. Nat Commun. 2019 Sep 25;10(1):4349. doi: 10.1038/s41467-019-12241-2. Nat Commun. 2019. PMID: 31554791 Free PMC article.
Putting the BRK on breast cancer: From molecular target to therapeutics.
Ang HL, Yuan Y, Lai X, Tan TZ, Wang L, Huang BB, Pandey V, Huang RY, Lobie PE, Goh BC, Sethi G, Yap CT, Chan CW, Lee SC, Kumar AP. Ang HL, et al. Among authors: kumar ap. Theranostics. 2021 Jan 1;11(3):1115-1128. doi: 10.7150/thno.49716. eCollection 2021. Theranostics. 2021. PMID: 33391524 Free PMC article. Review.
432 results