Kulkarni RN - Search Results

1

Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice.

De Jesus DF, Orime K, Kaminska D, Kimura T, Basile G, Wang CH, Haertle L, Riemens R, Brown NK, Hu J, Männistö V, Silva AM, Dirice E, Tseng YH, Haaf T, Pihlajamäki J, Kulkarni RN. De Jesus DF, et al. Among authors: kulkarni rn. J Clin Invest. 2020 May 1;130(5):2391-2407. doi: 10.1172/JCI127502. J Clin Invest. 2020. PMID: 32250344 Free PMC article.

2

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.

Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Mossa-Basha M, White MF. Hennige AM, et al. Among authors: kulkarni rn. J Clin Invest. 2003 Nov;112(10):1521-32. doi: 10.1172/JCI18581. J Clin Invest. 2003. PMID: 14617753 Free PMC article.

3

PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance.

Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR. Kulkarni RN, et al. J Clin Invest. 2004 Sep;114(6):828-36. doi: 10.1172/JCI21845. J Clin Invest. 2004. PMID: 15372107 Free PMC article.

4

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.

Gunton JE, Kulkarni RN, Yim S, Okada T, Hawthorne WJ, Tseng YH, Roberson RS, Ricordi C, O'Connell PJ, Gonzalez FJ, Kahn CR. Gunton JE, et al. Among authors: kulkarni rn. Cell. 2005 Aug 12;122(3):337-49. doi: 10.1016/j.cell.2005.05.027. Cell. 2005. PMID: 16096055 Free article.

5

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.

Okada T, Liew CW, Hu J, Hinault C, Michael MD, Krtzfeldt J, Yin C, Holzenberger M, Stoffel M, Kulkarni RN. Okada T, et al. Among authors: kulkarni rn. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8977-82. doi: 10.1073/pnas.0608703104. Epub 2007 Apr 6. Proc Natl Acad Sci U S A. 2007. PMID: 17416680 Free PMC article.

6

Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.

Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN. Morioka T, et al. Among authors: kulkarni rn. J Clin Invest. 2007 Oct;117(10):2860-8. doi: 10.1172/JCI30910. J Clin Invest. 2007. PMID: 17909627 Free PMC article.

7

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.

Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM. Handschin C, et al. Among authors: kulkarni rn. J Clin Invest. 2007 Nov;117(11):3463-74. doi: 10.1172/JCI31785. J Clin Invest. 2007. PMID: 17932564 Free PMC article.

8

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR. Tseng YH, et al. Among authors: kulkarni rn. Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221. Nature. 2008. PMID: 18719589 Free PMC article.

9

Differential expression of cell cycle proteins during ageing of pancreatic islet cells.

Hinault C, Hu J, Maier BF, Mirmira RG, Kulkarni RN. Hinault C, et al. Among authors: kulkarni rn. Diabetes Obes Metab. 2008 Nov;10 Suppl 4:136-46. doi: 10.1111/j.1463-1326.2008.00947.x. Diabetes Obes Metab. 2008. PMID: 18834441 Review.

10

Insulin signaling in alpha cells modulates glucagon secretion in vivo.

Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN. Kawamori D, et al. Among authors: kulkarni rn. Cell Metab. 2009 Apr;9(4):350-61. doi: 10.1016/j.cmet.2009.02.007. Cell Metab. 2009. PMID: 19356716 Free PMC article.

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