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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy.
Kranz LM, Diken M, Haas H, Kreiter S, Loquai C, Reuter KC, Meng M, Fritz D, Vascotto F, Hefesha H, Grunwitz C, Vormehr M, Hüsemann Y, Selmi A, Kuhn AN, Buck J, Derhovanessian E, Rae R, Attig S, Diekmann J, Jabulowsky RA, Heesch S, Hassel J, Langguth P, Grabbe S, Huber C, Türeci Ö, Sahin U. Kranz LM, et al. Among authors: kuhn an. Nature. 2016 Jun 16;534(7607):396-401. doi: 10.1038/nature18300. Epub 2016 Jun 1. Nature. 2016. PMID: 27281205
Exploiting the mutanome for tumor vaccination.
Castle JC, Kreiter S, Diekmann J, Löwer M, van de Roemer N, de Graaf J, Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM, Huber C, Türeci O, Sahin U. Castle JC, et al. Among authors: kuhn an. Cancer Res. 2012 Mar 1;72(5):1081-91. doi: 10.1158/0008-5472.CAN-11-3722. Epub 2012 Jan 11. Cancer Res. 2012. PMID: 22237626 Free article.
mRNA as a versatile tool for exogenous protein expression.
Kuhn AN, Beiβert T, Simon P, Vallazza B, Buck J, Davies BP, Tureci O, Sahin U. Kuhn AN, et al. Curr Gene Ther. 2012 Oct;12(5):347-61. doi: 10.2174/156652312802762536. Curr Gene Ther. 2012. PMID: 22827224 Review.
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.
Kowalska J, Wypijewska del Nogal A, Darzynkiewicz ZM, Buck J, Nicola C, Kuhn AN, Lukaszewicz M, Zuberek J, Strenkowska M, Ziemniak M, Maciejczyk M, Bojarska E, Rhoads RE, Darzynkiewicz E, Sahin U, Jemielity J. Kowalska J, et al. Among authors: kuhn an. Nucleic Acids Res. 2014;42(16):10245-64. doi: 10.1093/nar/gku757. Epub 2014 Aug 22. Nucleic Acids Res. 2014. PMID: 25150148 Free PMC article.
27 results