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Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo.
Wymann S, Mischnik M, Leong D, Ghosh S, Tan X, Cao H, Kuehnemuth B, Powers GA, Halder P, de Souza MJ, James HS, Tomasetig V, Lind H, Rossato P, Owczarek CM, Ow SY, Dower SK, Baz Morelli A, Rowe T, Hardy MP. Wymann S, et al. Among authors: kuehnemuth b. Biochem J. 2022 May 13;479(9):1007-1030. doi: 10.1042/BCJ20220054. Biochem J. 2022. PMID: 35470373
Tissue distribution of rIX-FP after intravenous application to rodents.
Herrmann S, Doerr B, May F, Kuehnemuth B, Cherpokova D, Herzog E, Dickneite G, Nolte MW. Herrmann S, et al. Among authors: kuehnemuth b. J Thromb Haemost. 2020 Dec;18(12):3194-3202. doi: 10.1111/jth.15069. Epub 2020 Oct 25. J Thromb Haemost. 2020. PMID: 32810892 Free article.