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The FZD7-TWIST1 axis is responsible for anoikis resistance and tumorigenesis in ovarian carcinoma.
Mol Oncol. 2019 Apr;13(4):757-780. doi: 10.1002/1878-0261.12425. Epub 2019 Jan 19.
Mol Oncol. 2019.
PMID: 30548372
Free PMC article.
Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120).
Huang RY, Kuay KT, Tan TZ, Asad M, Tang HM, Ng AH, Ye J, Chung VY, Thiery JP.
Huang RY, et al. Among authors: kuay kt.
Oncotarget. 2015 Sep 8;6(26):22098-113. doi: 10.18632/oncotarget.4300.
Oncotarget. 2015.
PMID: 26061747
Free PMC article.
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GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification.
Chung VY, Tan TZ, Tan M, Wong MK, Kuay KT, Yang Z, Ye J, Muller J, Koh CM, Guccione E, Thiery JP, Huang RY.
Chung VY, et al. Among authors: kuay kt.
Sci Rep. 2016 Feb 18;6:19943. doi: 10.1038/srep19943.
Sci Rep. 2016.
PMID: 26887977
Free PMC article.
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An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).
Huang RY, Wong MK, Tan TZ, Kuay KT, Ng AH, Chung VY, Chu YS, Matsumura N, Lai HC, Lee YF, Sim WJ, Chai C, Pietschmann E, Mori S, Low JJ, Choolani M, Thiery JP.
Huang RY, et al. Among authors: kuay kt.
Cell Death Dis. 2013 Nov 7;4(11):e915. doi: 10.1038/cddis.2013.442.
Cell Death Dis. 2013.
PMID: 24201814
Free PMC article.
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An epithelial marker promoter induction screen identifies histone deacetylase inhibitors to restore epithelial differentiation and abolishes anchorage independence growth in cancers.
Tang HM, Kuay KT, Koh PF, Asad M, Tan TZ, Chung VY, Lee SC, Thiery JP, Huang RJ.
Tang HM, et al. Among authors: kuay kt.
Cell Death Discov. 2016 Jun 13;2:16041. doi: 10.1038/cddiscovery.2016.41. eCollection 2016.
Cell Death Discov. 2016.
PMID: 27551531
Free PMC article.
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