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X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Günther S, Reinke PYA, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schlünzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Doyle JJ, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A. Günther S, et al. Among authors: krichel b. Science. 2021 May 7;372(6542):642-646. doi: 10.1126/science.abf7945. Epub 2021 Apr 2. Science. 2021. PMID: 33811162 Free PMC article.
Processing of the SARS-CoV pp1a/ab nsp7-10 region.
Krichel B, Falke S, Hilgenfeld R, Redecke L, Uetrecht C. Krichel B, et al. Biochem J. 2020 Mar 13;477(5):1009-1019. doi: 10.1042/BCJ20200029. Biochem J. 2020. PMID: 32083638 Free PMC article.
Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes.
Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C. Krichel B, et al. Sci Adv. 2021 Mar 3;7(10):eabf1004. doi: 10.1126/sciadv.abf1004. Print 2021 Mar. Sci Adv. 2021. PMID: 33658206 Free PMC article.
Structural mass spectrometry goes viral.
Dülfer J, Kadek A, Kopicki JD, Krichel B, Uetrecht C. Dülfer J, et al. Among authors: krichel b. Adv Virus Res. 2019;105:189-238. doi: 10.1016/bs.aivir.2019.07.003. Epub 2019 Aug 27. Adv Virus Res. 2019. PMID: 31522705
Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes.
Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C. Krichel B, et al. bioRxiv [Preprint]. 2020 Oct 7:2020.09.30.320762. doi: 10.1101/2020.09.30.320762. bioRxiv. 2020. PMID: 33024972 Free PMC article. Updated. Preprint.
The crystal structure of mycobacterial epoxide hydrolase A.
Schulz EC, Henderson SR, Illarionov B, Crosskey T, Southall SM, Krichel B, Uetrecht C, Fischer M, Wilmanns M. Schulz EC, et al. Among authors: krichel b. Sci Rep. 2020 Oct 6;10(1):16539. doi: 10.1038/s41598-020-73452-y. Sci Rep. 2020. PMID: 33024154 Free PMC article.
Structure and target interaction of a G-quadruplex RNA-aptamer.
Szameit K, Berg K, Kruspe S, Valentini E, Magbanua E, Kwiatkowski M, Chauvot de Beauchêne I, Krichel B, Schamoni K, Uetrecht C, Svergun DI, Schlüter H, Zacharias M, Hahn U. Szameit K, et al. Among authors: krichel b. RNA Biol. 2016 Oct 2;13(10):973-987. doi: 10.1080/15476286.2016.1212151. Epub 2016 Jul 29. RNA Biol. 2016. PMID: 27471797 Free PMC article.
MASH Native: a unified solution for native top-down proteomics data processing.
Larson EJ, Pergande MR, Moss ME, Rossler KJ, Wenger RK, Krichel B, Josyer H, Melby JA, Roberts DS, Pike K, Shi Z, Chan HJ, Knight B, Rogers HT, Brown KA, Ong IM, Jeong K, Marty MT, McIlwain SJ, Ge Y. Larson EJ, et al. Among authors: krichel b. Bioinformatics. 2023 Jun 1;39(6):btad359. doi: 10.1093/bioinformatics/btad359. Bioinformatics. 2023. PMID: 37294807 Free PMC article.
11 results