Kreiter S - Search Results

1

Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.

Muik A, Garralda E, Altintas I, Gieseke F, Geva R, Ben-Ami E, Maurice-Dror C, Calvo E, LoRusso PM, Alonso G, Rodriguez-Ruiz ME, Schoedel KB, Blum JM, Sänger B, Salcedo TW, Burm SM, Stanganello E, Verzijl D, Vascotto F, Sette A, Quinkhardt J, Plantinga TS, Toker A, van den Brink EN, Fereshteh M, Diken M, Satijn D, Kreiter S, Breij ECW, Bajaj G, Lagkadinou E, Sasser K, Türeci Ö, Forssmann U, Ahmadi T, Şahin U, Jure-Kunkel M, Melero I. Muik A, et al. Among authors: kreiter s. Cancer Discov. 2022 May 2;12(5):1248-1265. doi: 10.1158/2159-8290.CD-21-1345. Cancer Discov. 2022. PMID: 35176764 Free PMC article. Clinical Trial.

2

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

Holtkamp S, Kreiter S, Selmi A, Simon P, Koslowski M, Huber C, Türeci O, Sahin U. Holtkamp S, et al. Among authors: kreiter s. Blood. 2006 Dec 15;108(13):4009-17. doi: 10.1182/blood-2006-04-015024. Epub 2006 Aug 29. Blood. 2006. PMID: 16940422 Free article.

3

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA.

Kreiter S, Konrad T, Sester M, Huber C, Türeci O, Sahin U. Kreiter S, et al. Cancer Immunol Immunother. 2007 Oct;56(10):1577-87. doi: 10.1007/s00262-007-0302-7. Epub 2007 Mar 15. Cancer Immunol Immunother. 2007. PMID: 17361438 Free PMC article.

4

Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals.

Kreiter S, Selmi A, Diken M, Sebastian M, Osterloh P, Schild H, Huber C, Türeci O, Sahin U. Kreiter S, et al. J Immunol. 2008 Jan 1;180(1):309-18. doi: 10.4049/jimmunol.180.1.309. J Immunol. 2008. PMID: 18097032

5

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo.

Kuhn AN, Diken M, Kreiter S, Selmi A, Kowalska J, Jemielity J, Darzynkiewicz E, Huber C, Türeci O, Sahin U. Kuhn AN, et al. Among authors: kreiter s. Gene Ther. 2010 Aug;17(8):961-71. doi: 10.1038/gt.2010.52. Epub 2010 Apr 22. Gene Ther. 2010. PMID: 20410931

6

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

Kreiter S, Selmi A, Diken M, Koslowski M, Britten CM, Huber C, Türeci O, Sahin U. Kreiter S, et al. Cancer Res. 2010 Nov 15;70(22):9031-40. doi: 10.1158/0008-5472.CAN-10-0699. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045153

7

Highly specific auto-antibodies against claudin-18 isoform 2 induced by a chimeric HBcAg virus-like particle vaccine kill tumor cells and inhibit the growth of lung metastases.

Klamp T, Schumacher J, Huber G, Kühne C, Meissner U, Selmi A, Hiller T, Kreiter S, Markl J, Türeci Ö, Sahin U. Klamp T, et al. Among authors: kreiter s. Cancer Res. 2011 Jan 15;71(2):516-27. doi: 10.1158/0008-5472.CAN-10-2292. Epub 2011 Jan 11. Cancer Res. 2011. PMID: 21224362

8

Determinants of intracellular RNA pharmacokinetics: Implications for RNA-based immunotherapeutics.

Kuhn AN, Diken M, Kreiter S, Vallazza B, Türeci Ö, Sahin U. Kuhn AN, et al. Among authors: kreiter s. RNA Biol. 2011 Jan-Feb;8(1):35-43. doi: 10.4161/rna.8.1.13767. Epub 2011 Jan 1. RNA Biol. 2011. PMID: 21289486

9

Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation.

Diken M, Kreiter S, Selmi A, Britten CM, Huber C, Türeci Ö, Sahin U. Diken M, et al. Among authors: kreiter s. Gene Ther. 2011 Jul;18(7):702-8. doi: 10.1038/gt.2011.17. Epub 2011 Mar 3. Gene Ther. 2011. PMID: 21368901

10

Tumor vaccination using messenger RNA: prospects of a future therapy.

Kreiter S, Diken M, Selmi A, Türeci Ö, Sahin U. Kreiter S, et al. Curr Opin Immunol. 2011 Jun;23(3):399-406. doi: 10.1016/j.coi.2011.03.007. Epub 2011 Apr 13. Curr Opin Immunol. 2011. PMID: 21497074 Review.

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