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Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19.
Zhu B, Wei X, Narasimhan H, Qian W, Zhang R, Cheon IS, Wu Y, Li C, Jones RG, Kaplan MH, Vassallo RA, Braciale TJ, Somerville L, Colca JR, Pandey A, Jackson PEH, Mann BJ, Krawczyk CM, Sturek JM, Sun J. Zhu B, et al. Among authors: krawczyk cm. Sci Immunol. 2023 Apr 14;8(82):eadf0348. doi: 10.1126/sciimmunol.adf0348. Epub 2023 Apr 14. Sci Immunol. 2023. PMID: 36821695 Free PMC article.
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling.
Irie-Sasaki J, Sasaki T, Matsumoto W, Opavsky A, Cheng M, Welstead G, Griffiths E, Krawczyk C, Richardson CD, Aitken K, Iscove N, Koretzky G, Johnson P, Liu P, Rothstein DM, Penninger JM. Irie-Sasaki J, et al. Nature. 2001 Jan 18;409(6818):349-54. doi: 10.1038/35053086. Nature. 2001. PMID: 11201744
The Summit for Cancer Immunotherapy (Summit4CI), June 26-29, 2016 Halifax, Canada.
Wouters MCA, Laumont CM, Chen B, Han SJ, Matuszewska K, Potts K, Boudreau JE, Krawczyk CM. Wouters MCA, et al. Among authors: krawczyk cm. Cancer Immunol Immunother. 2017 Jun;66(6):811-818. doi: 10.1007/s00262-017-1996-9. Epub 2017 Apr 13. Cancer Immunol Immunother. 2017. PMID: 28409191 Free PMC article. No abstract available.
The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence.
Boukhaled GM, Cordeiro B, Deblois G, Dimitrov V, Bailey SD, Holowka T, Domi A, Guak H, Chiu HH, Everts B, Pearce EJ, Lupien M, White JH, Krawczyk CM. Boukhaled GM, et al. Among authors: krawczyk cm. Cell Rep. 2016 Aug 16;16(7):1829-37. doi: 10.1016/j.celrep.2016.07.026. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498878 Free article.
64 results