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Page 1
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT. Cohen F, et al. Among authors: krause km. ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5. ChemMedChem. 2019. PMID: 31283109
Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa.
Krause KM, Haglund CM, Hebner C, Serio AW, Lee G, Nieto V, Cohen F, Kane TR, Machajewski TD, Hildebrandt D, Pillar C, Thwaites M, Hall D, Miesel L, Hackel M, Burek A, Andrews LD, Armstrong E, Swem L, Jubb A, Cirz RT. Krause KM, et al. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00977-19. doi: 10.1128/AAC.00977-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451507 Free PMC article.
Aminoglycosides: An Overview.
Krause KM, Serio AW, Kane TR, Connolly LE. Krause KM, et al. Cold Spring Harb Perspect Med. 2016 Jun 1;6(6):a027029. doi: 10.1101/cshperspect.a027029. Cold Spring Harb Perspect Med. 2016. PMID: 27252397 Free PMC article. Review.
A multivalent approach to drug discovery for novel antibiotics.
Long DD, Aggen JB, Christensen BG, Judice JK, Hegde SS, Kaniga K, Krause KM, Linsell MS, Moran EJ, Pace JL. Long DD, et al. Among authors: krause km. J Antibiot (Tokyo). 2008 Oct;61(10):595-602. doi: 10.1038/ja.2008.79. J Antibiot (Tokyo). 2008. PMID: 19168973
Activity of plazomicin compared with other aminoglycosides against isolates from European and adjacent countries, including Enterobacteriaceae molecularly characterized for aminoglycoside-modifying enzymes and other resistance mechanisms.
Castanheira M, Deshpande LM, Woosley LN, Serio AW, Krause KM, Flamm RK. Castanheira M, et al. Among authors: krause km. J Antimicrob Chemother. 2018 Dec 1;73(12):3346-3354. doi: 10.1093/jac/dky344. J Antimicrob Chemother. 2018. PMID: 30219857
In Vitro Activity of Plazomicin against Gram-Negative and Gram-Positive Isolates Collected from U.S. Hospitals and Comparative Activities of Aminoglycosides against Carbapenem-Resistant Enterobacteriaceae and Isolates Carrying Carbapenemase Genes.
Castanheira M, Davis AP, Mendes RE, Serio AW, Krause KM, Flamm RK. Castanheira M, et al. Among authors: krause km. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00313-18. doi: 10.1128/AAC.00313-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29866862 Free PMC article.
Exploring the positional attachment of glycopeptide/beta-lactam heterodimers.
Long DD, Aggen JB, Chinn J, Choi SK, Christensen BG, Fatheree PR, Green D, Hegde SS, Judice JK, Kaniga K, Krause KM, Leadbetter M, Linsell MS, Marquess DG, Moran EJ, Nodwell MB, Pace JL, Trapp SG, Turner SD. Long DD, et al. Among authors: krause km. J Antibiot (Tokyo). 2008 Oct;61(10):603-14. doi: 10.1038/ja.2008.80. J Antibiot (Tokyo). 2008. PMID: 19168974
109 results