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The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis.
Müller A, Dickmanns A, Resch C, Schäkel K, Hailfinger S, Dobbelstein M, Schulze-Osthoff K, Kramer D. Müller A, et al. Among authors: kramer d. J Clin Invest. 2020 Nov 2;130(11):5765-5781. doi: 10.1172/JCI134217. J Clin Invest. 2020. PMID: 32701505 Free PMC article.
TAp73 is essential for germ cell adhesion and maturation in testis.
Holembowski L, Kramer D, Riedel D, Sordella R, Nemajerova A, Dobbelstein M, Moll UM. Holembowski L, et al. Among authors: kramer d. J Cell Biol. 2014 Mar 31;204(7):1173-90. doi: 10.1083/jcb.201306066. Epub 2014 Mar 24. J Cell Biol. 2014. PMID: 24662569 Free PMC article.
MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
Wienken M, Dickmanns A, Nemajerova A, Kramer D, Najafova Z, Weiss M, Karpiuk O, Kassem M, Zhang Y, Lozano G, Johnsen SA, Moll UM, Zhang X, Dobbelstein M. Wienken M, et al. Among authors: kramer d. Mol Cell. 2016 Jan 7;61(1):68-83. doi: 10.1016/j.molcel.2015.12.008. Epub 2015 Dec 31. Mol Cell. 2016. PMID: 26748827 Free PMC article.
Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation.
Schwenck J, Mehling R, Thaiss WM, Kramer D, Menendez IG, Öz HH, Hartl D, Schulze-Osthoff K, Hailfinger S, Ghoreschi K, Quintanilla-Martinez L, Carlsen H, Röcken M, Pichler BJ, Kneilling M. Schwenck J, et al. Among authors: kramer d. Mol Imaging Biol. 2020 Jun;22(3):504-514. doi: 10.1007/s11307-019-01412-8. Mol Imaging Biol. 2020. PMID: 31482411 Free PMC article.
Keratinocyte-derived IκBζ drives psoriasis and associated systemic inflammation.
Lorscheid S, Müller A, Löffler J, Resch C, Bucher P, Kurschus FC, Waisman A, Schäkel K, Hailfinger S, Schulze-Osthoff K, Kramer D. Lorscheid S, et al. Among authors: kramer d. JCI Insight. 2019 Nov 14;4(22):e130835. doi: 10.1172/jci.insight.130835. JCI Insight. 2019. PMID: 31622280 Free PMC article.
1,388 results