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Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials.
Lancet Infect Dis. 2019 Mar;19(3):265-274. doi: 10.1016/S1473-3099(18)30614-5. Epub 2019 Jan 29.
Lancet Infect Dis. 2019.
PMID: 30709665
Free article.
Susceptibility of Clostridium difficile isolates from a Phase 2 clinical trial of cadazolid and vancomycin in C. difficile infection.
Gerding DN, Hecht DW, Louie T, Nord CE, Talbot GH, Cornely OA, Buitrago M, Best E, Sambol S, Osmolski JR, Kracker H, Locher HH, Charef P, Wilcox M.
Gerding DN, et al. Among authors: kracker h.
J Antimicrob Chemother. 2016 Jan;71(1):213-9. doi: 10.1093/jac/dkv300. Epub 2015 Oct 3.
J Antimicrob Chemother. 2016.
PMID: 26433782
Free PMC article.
Clinical Trial.
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Multicenter, Double-Blind, Randomized, Phase 2 Study Evaluating the Novel Antibiotic Cadazolid in Patients with Clostridium difficile Infection.
Louie T, Nord CE, Talbot GH, Wilcox M, Gerding DN, Buitrago M, Kracker H, Charef P, Cornely OA.
Louie T, et al. Among authors: kracker h.
Antimicrob Agents Chemother. 2015 Oct;59(10):6266-73. doi: 10.1128/AAC.00504-15. Epub 2015 Jul 27.
Antimicrob Agents Chemother. 2015.
PMID: 26248357
Free PMC article.
Clinical Trial.
Item in Clipboard
Efficacy and safety of the dual L- and T-type calcium channel blocker, ACT-280778: a proof-of-concept study in patients with mild-to-moderate essential hypertension.
Dingemanse J, Otasevic P, Shakeri-Nejad K, Klainman E, Putnikovic B, Kracker H, Mueller MS, Zimlichman R.
Dingemanse J, et al. Among authors: kracker h.
J Hum Hypertens. 2015 Apr;29(4):229-35. doi: 10.1038/jhh.2014.79. Epub 2014 Sep 18.
J Hum Hypertens. 2015.
PMID: 25231512
Clinical Trial.
Item in Clipboard
An exposure-response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis.
Valenzuela B, Olsson Gisleskog P, Poggesi I, Sidorenko T, Burcklen M, Kracker H, Pérez-Ruixo JJ.
Valenzuela B, et al. Among authors: kracker h.
CPT Pharmacometrics Syst Pharmacol. 2022 Oct;11(10):1294-1304. doi: 10.1002/psp4.12778. Epub 2022 Sep 1.
CPT Pharmacometrics Syst Pharmacol. 2022.
PMID: 36047474
Free PMC article.
Clinical Trial.
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Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study: A Randomized Clinical Trial.
Kappos L, Fox RJ, Burcklen M, Freedman MS, Havrdová EK, Hennessy B, Hohlfeld R, Lublin F, Montalban X, Pozzilli C, Scherz T, D'Ambrosio D, Linscheid P, Vaclavkova A, Pirozek-Lawniczek M, Kracker H, Sprenger T.
Kappos L, et al. Among authors: kracker h.
JAMA Neurol. 2021 May 1;78(5):558-567. doi: 10.1001/jamaneurol.2021.0405.
JAMA Neurol. 2021.
PMID: 33779698
Free PMC article.
Clinical Trial.
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Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: Model-Based Meta-Analyses for Confirmed Disability Accumulation and Annualized Relapse Rate.
Hennessy B, Zierhut ML, Kracker H, Keenan A, Sidorenko T.
Hennessy B, et al. Among authors: kracker h.
Mult Scler Relat Disord. 2022 Aug;64:103908. doi: 10.1016/j.msard.2022.103908. Epub 2022 May 23.
Mult Scler Relat Disord. 2022.
PMID: 35803162
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