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The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.
Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, Ekici AB, Major T, Aust O, Weidner D, Fischer A, Andes FT, Stanojevic Z, Trajkovic V, Herrmann M, Korb-Pap A, Wank I, Hess A, Winter J, Wixler V, Distler J, Steiner G, Kiener HP, Frey B, Kling L, Raza K, Frey S, Kleyer A, Bäuerle T, Hughes TR, Grüneboom A, Steffen U, Krönke G, Croft AP, Filer A, Köhl J, Klein K, Buckley CD, Schett G, Mougiakakos D, Hoffmann MH. Friščić J, et al. Among authors: kruger r. Immunity. 2021 May 11;54(5):1002-1021.e10. doi: 10.1016/j.immuni.2021.03.003. Epub 2021 Mar 23. Immunity. 2021. PMID: 33761330 Free article.
Reset of Inflammatory Priming of Joint Tissue and Reduction of the Severity of Arthritis Flares by Bromodomain Inhibition.
Friščić J, Reinwald C, Böttcher M, Houtman M, Euler M, Chen X, Walker KI, Kirchner P, Zhu H, Wirth B, Weidner D, Krüger R, Trajkovic V, Ekici AB, Klein K, Mougiakakos D, Ospelt C, Schett G, Hoffmann MH. Friščić J, et al. Among authors: kruger r. Arthritis Rheumatol. 2023 Apr;75(4):517-532. doi: 10.1002/art.42378. Epub 2023 Feb 2. Arthritis Rheumatol. 2023. PMID: 36245290 Free article.
Hypoxia induces polycystin-1 expression in the renal epithelium.
Grampp S, Kraus A, Skoczynski K, Schiffer M, Krüger R, Naas S, Schödel J, Buchholz B. Grampp S, et al. Among authors: kruger r. R Soc Open Sci. 2023 May 17;10(5):220992. doi: 10.1098/rsos.220992. eCollection 2023 May. R Soc Open Sci. 2023. PMID: 37206967 Free PMC article.
Hypoxia hits APOL1 in the kidney.
Grampp S, Krüger R, Lauer V, Uebel S, Knaup KX, Naas J, Höffken V, Weide T, Schiffer M, Naas S, Schödel J. Grampp S, et al. Among authors: kruger r. Kidney Int. 2023 Jul;104(1):53-60. doi: 10.1016/j.kint.2023.03.035. Epub 2023 Apr 23. Kidney Int. 2023. PMID: 37098381 Free article.
Hypoxia controls expression of kidney-pathogenic MUC1 variants.
Naas S, Krüger R, Knaup KX, Naas J, Grampp S, Schiffer M, Wiesener M, Schödel J. Naas S, et al. Among authors: kruger r. Life Sci Alliance. 2023 Jun 14;6(9):e202302078. doi: 10.26508/lsa.202302078. Print 2023 Sep. Life Sci Alliance. 2023. PMID: 37316299 Free PMC article.
1,063 results