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Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy.
Grosch M, Schraft L, Chan A, Küchenhoff L, Rapti K, Ferreira AM, Kornienko J, Li S, Radke MH, Krämer C, Clauder-Münster S, Perlas E, Backs J, Gotthardt M, Dieterich C, van den Hoogenhof MMG, Grimm D, Steinmetz LM. Grosch M, et al. Among authors: kramer c. Nat Commun. 2023 Jun 22;14(1):3714. doi: 10.1038/s41467-023-39352-1. Nat Commun. 2023. PMID: 37349314 Free PMC article.
Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders.
El Andari J, Renaud-Gabardos E, Tulalamba W, Weinmann J, Mangin L, Pham QH, Hille S, Bennett A, Attebi E, Bourges E, Leborgne C, Guerchet N, Fakhiri J, Krämer C, Wiedtke E, McKenna R, Guianvarc'h L, Toueille M, Ronzitti G, Hebben M, Mingozzi F, VandenDriessche T, Agbandje-McKenna M, Müller OJ, Chuah MK, Buj-Bello A, Grimm D. El Andari J, et al. Among authors: kramer c. Sci Adv. 2022 Sep 23;8(38):eabn4704. doi: 10.1126/sciadv.abn4704. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129972 Free PMC article.
Cardiometabolic biomarker patterns associated with cardiac MRI defined fibrosis and microvascular dysfunction in patients with heart failure with preserved ejection fraction.
Siggins C, Pan JA, Löffler AI, Yang Y, Shaw PW, Balfour PC Jr, Epstein FH, Gan LM, Kramer CM, Keeley EC, Salerno M. Siggins C, et al. Among authors: kramer cm. Front Cardiovasc Med. 2024 Mar 4;11:1334226. doi: 10.3389/fcvm.2024.1334226. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38500750 Free PMC article.
1,159 results