Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice.
Kozel PJ, Davis RR, Krieg EF, Shull GE, Erway LC.
Kozel PJ, et al.
Hear Res. 2002 Feb;164(1-2):231-9. doi: 10.1016/s0378-5955(01)00420-8.
Hear Res. 2002.
PMID: 11950541
Mice homozygous for a null mutation in the plasma membrane Ca2+-ATPase isoform 2 (PMCA2) gene are deaf (Kozel et al., 1998). PMCA2 is expressed on outer hair cell stereocilia (Furuta et al., 1998). ...Fifteen days following an 8 h, 113 dB noise exposure, the Pmca2+/- mice …
Mice homozygous for a null mutation in the plasma membrane Ca2+-ATPase isoform 2 (PMCA2) gene are deaf (Kozel et al., 1998). PMCA2 is …