Kovalenko OP - Search Results

1

The Dual Role of the 2'-OH Group of A76 tRNA^Tyr in the Prevention of d-tyrosine Mistranslation.

Rybak MY, Kovalenko OP, Tukalo MA. Rybak MY, et al. Among authors: kovalenko op. J Mol Biol. 2018 Aug 17;430(17):2670-2676. doi: 10.1016/j.jmb.2018.06.036. Epub 2018 Jun 25. J Mol Biol. 2018. PMID: 29953888

2

[Comparative study of the reactability of phosphoric acid residues in tRNA(Ser) and tRNA(Leu) from Thermus thermophilus].

Kovalenko OP, Petrushenko ZM, Kriklivyĭ IA, Iaremchuk AD, Tukalo MA. Kovalenko OP, et al. Bioorg Khim. 1999 Oct;25(10):768-73. Bioorg Khim. 1999. PMID: 10645480 Russian.

3

Substrate-assisted mechanism of catalytic hydrolysis of misaminoacylated tRNA required for protein synthesis fidelity.

Ilchenko MM, Rybak MY, Rayevsky AV, Kovalenko OP, Dubey IY, Tukalo MA. Ilchenko MM, et al. Among authors: kovalenko op. Biochem J. 2019 Feb 28;476(4):719-732. doi: 10.1042/BCJ20180910. Biochem J. 2019. PMID: 30718305

4

Dual-targeted hit identification using pharmacophore screening.

Volynets GP, Starosyla SA, Rybak MY, Bdzhola VG, Kovalenko OP, Vdovin VS, Yarmoluk SM, Tukalo MA. Volynets GP, et al. Among authors: kovalenko op. J Comput Aided Mol Des. 2019 Nov;33(11):955-964. doi: 10.1007/s10822-019-00245-5. Epub 2019 Nov 6. J Comput Aided Mol Des. 2019. PMID: 31691918

5

Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines.

Kovalenko OP, Volynets GP, Rybak MY, Starosyla SA, Gudzera OI, Lukashov SS, Bdzhola VG, Yarmoluk SM, Boshoff HI, Tukalo MA. Kovalenko OP, et al. Medchemcomm. 2019 Nov 28;10(12):2161-2169. doi: 10.1039/c9md00347a. eCollection 2019 Dec 1. Medchemcomm. 2019. PMID: 32206244 Free PMC article.

6

Developing a comprehensive solution aimed to disrupt LARS1/RagD protein-protein interaction.

Raevsky A, Kovalenko O, Bulgakov E, Sharifi M, Volochnyuk D, Tukalo M. Raevsky A, et al. J Biomol Struct Dyn. 2024 Jan-Feb;42(2):747-758. doi: 10.1080/07391102.2023.2194996. Epub 2023 Mar 30. J Biomol Struct Dyn. 2024. PMID: 36995308

7

Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase.

Gudzera OI, Golub AG, Bdzhola VG, Volynets GP, Lukashov SS, Kovalenko OP, Kriklivyi IA, Yaremchuk AD, Starosyla SA, Yarmoluk SM, Tukalo MA. Gudzera OI, et al. Among authors: kovalenko op. Bioorg Med Chem. 2016 Mar 1;24(5):1023-31. doi: 10.1016/j.bmc.2016.01.028. Epub 2016 Jan 16. Bioorg Med Chem. 2016. PMID: 26822568

8

Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one.

Gudzera OI, Golub AG, Bdzhola VG, Volynets GP, Kovalenko OP, Boyarshin KS, Yaremchuk AD, Protopopov MV, Yarmoluk SM, Tukalo MA. Gudzera OI, et al. Among authors: kovalenko op. J Enzyme Inhib Med Chem. 2016;31(sup2):201-207. doi: 10.1080/14756366.2016.1190712. Epub 2016 May 31. J Enzyme Inhib Med Chem. 2016. PMID: 27241561

9

Mutation Ala2-->Ser destabilizes intersubunit interactions in the molecular chaperone GroEL.

Horovitz A, Bochkareva ES, Kovalenko O, Girshovich AS. Horovitz A, et al. J Mol Biol. 1993 May 5;231(1):58-64. doi: 10.1006/jmbi.1993.1256. J Mol Biol. 1993. PMID: 8098773

10

Residue lysine-34 in GroES modulates allosteric transitions in GroEL.

Kovalenko O, Yifrach O, Horovitz A. Kovalenko O, et al. Biochemistry. 1994 Dec 20;33(50):14974-8. doi: 10.1021/bi00254a004. Biochemistry. 1994. PMID: 7999753

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