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A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity.
Sci Transl Med. 2022 Dec 21;14(676):eabj4221. doi: 10.1126/scitranslmed.abj4221. Epub 2022 Dec 21.
Sci Transl Med. 2022.
PMID: 36542691
Reducing dynamin 2 expression rescues X-linked centronuclear myopathy.
Cowling BS, Chevremont T, Prokic I, Kretz C, Ferry A, Coirault C, Koutsopoulos O, Laugel V, Romero NB, Laporte J.
Cowling BS, et al. Among authors: koutsopoulos o.
J Clin Invest. 2014 Mar;124(3):1350-63. doi: 10.1172/JCI71206. Epub 2014 Feb 24.
J Clin Invest. 2014.
PMID: 24569376
Free PMC article.
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Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome.
Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J.
Koutsopoulos OS, et al.
Eur J Hum Genet. 2013 Jun;21(6):637-42. doi: 10.1038/ejhg.2012.226. Epub 2012 Oct 24.
Eur J Hum Genet. 2013.
PMID: 23092955
Free PMC article.
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Mild functional differences of dynamin 2 mutations associated to centronuclear myopathy and Charcot-Marie Tooth peripheral neuropathy.
Koutsopoulos OS, Koch C, Tosch V, Böhm J, North KN, Laporte J.
Koutsopoulos OS, et al.
PLoS One. 2011;6(11):e27498. doi: 10.1371/journal.pone.0027498. Epub 2011 Nov 11.
PLoS One. 2011.
PMID: 22096584
Free PMC article.
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MiD49 and MiD51, new components of the mitochondrial fission machinery.
Palmer CS, Osellame LD, Laine D, Koutsopoulos OS, Frazier AE, Ryan MT.
Palmer CS, et al. Among authors: koutsopoulos os.
EMBO Rep. 2011 Jun;12(6):565-73. doi: 10.1038/embor.2011.54. Epub 2011 Apr 21.
EMBO Rep. 2011.
PMID: 21508961
Free PMC article.
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Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks.
Koutsopoulos OS, Laine D, Osellame L, Chudakov DM, Parton RG, Frazier AE, Ryan MT.
Koutsopoulos OS, et al.
Biochim Biophys Acta. 2010 May;1803(5):564-74. doi: 10.1016/j.bbamcr.2010.03.006. Epub 2010 Mar 15.
Biochim Biophys Acta. 2010.
PMID: 20230862
Free article.
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Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology.
Stojanovski D, Koutsopoulos OS, Okamoto K, Ryan MT.
Stojanovski D, et al. Among authors: koutsopoulos os.
J Cell Sci. 2004 Mar 1;117(Pt 7):1201-10. doi: 10.1242/jcs.01058.
J Cell Sci. 2004.
PMID: 14996942
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