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NADPH-quinone oxidoreductase-1 mediates Benzo-[a]-pyrene-1,6-quinone-induced cytotoxicity and reactive oxygen species production in human EA.hy926 endothelial cells.
Toxicol Appl Pharmacol. 2020 Oct 1;404:115180. doi: 10.1016/j.taap.2020.115180. Epub 2020 Jul 31.
Toxicol Appl Pharmacol. 2020.
PMID: 32739527
Reactive oxygen species production by BP-1,6-quinone and its effects on the endothelial dysfunction: Involvement of the mitochondria.
Shukla H, Chitrakar R, Bibi HA, Gaje G, Koucheki A, Trush MA, Zhu H, Li YR, Jia Z.
Shukla H, et al. Among authors: koucheki a.
Toxicol Lett. 2020 Apr 1;322:120-130. doi: 10.1016/j.toxlet.2020.01.011. Epub 2020 Jan 14.
Toxicol Lett. 2020.
PMID: 31953210
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Targeting glutathione with the triterpenoid CDDO-Im protects against benzo-a-pyrene-1,6-quinone-induced cytotoxicity in endothelial cells.
Shukla H, Lee HY, Koucheki A, Bibi HA, Gaje G, Sun X, Zhu H, Li YR, Jia Z.
Shukla H, et al. Among authors: koucheki a.
Mol Cell Biochem. 2020 Nov;474(1-2):27-39. doi: 10.1007/s11010-020-03831-6. Epub 2020 Jul 27.
Mol Cell Biochem. 2020.
PMID: 32715408
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