Kosinski JR - Search Results

1

Effects of peripherally administered neuromedin U on energy and glucose homeostasis.

Peier AM, Desai K, Hubert J, Du X, Yang L, Qian Y, Kosinski JR, Metzger JM, Pocai A, Nawrocki AR, Langdon RB, Marsh DJ. Peier AM, et al. Among authors: kosinski jr. Endocrinology. 2011 Jul;152(7):2644-54. doi: 10.1210/en.2010-1463. Epub 2011 May 17. Endocrinology. 2011. PMID: 21586559

2

The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2).

Peier A, Kosinski J, Cox-York K, Qian Y, Desai K, Feng Y, Trivedi P, Hastings N, Marsh DJ. Peier A, et al. Endocrinology. 2009 Jul;150(7):3101-9. doi: 10.1210/en.2008-1772. Epub 2009 Mar 26. Endocrinology. 2009. PMID: 19324999 Free PMC article.

3

The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin.

Kosinski JR, Hubert J, Carrington PE, Chicchi GG, Mu J, Miller C, Cao J, Bianchi E, Pessi A, Sinharoy R, Marsh DJ, Pocai A. Kosinski JR, et al. Obesity (Silver Spring). 2012 Aug;20(8):1566-71. doi: 10.1038/oby.2012.67. Epub 2012 Mar 16. Obesity (Silver Spring). 2012. PMID: 22421924 Free PMC article.

4

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

Lin HV, Frassetto A, Kowalik EJ Jr, Nawrocki AR, Lu MM, Kosinski JR, Hubert JA, Szeto D, Yao X, Forrest G, Marsh DJ. Lin HV, et al. Among authors: kosinski jr. PLoS One. 2012;7(4):e35240. doi: 10.1371/journal.pone.0035240. Epub 2012 Apr 10. PLoS One. 2012. PMID: 22506074 Free PMC article.

5

Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.

Du X, Kosinski JR, Lao J, Shen X, Petrov A, Chicchi GG, Eiermann GJ, Pocai A. Du X, et al. Among authors: kosinski jr. Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E265-71. doi: 10.1152/ajpendo.00142.2012. Epub 2012 May 22. Am J Physiol Endocrinol Metab. 2012. PMID: 22621866 Free article.

6

Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.

Guan XM, Chen H, Dobbelaar PH, Dong Y, Fong TM, Gagen K, Gorski J, He S, Howard AD, Jian T, Jiang M, Kan Y, Kelly TM, Kosinski J, Lin LS, Liu J, Marsh DJ, Metzger JM, Miller R, Nargund RP, Palyha O, Shearman L, Shen Z, Stearns R, Strack AM, Stribling S, Tang YS, Wang SP, White A, Yu H, Reitman ML. Guan XM, et al. Cell Metab. 2010 Feb 3;11(2):101-12. doi: 10.1016/j.cmet.2009.12.008. Epub 2010 Jan 21. Cell Metab. 2010. PMID: 20096642 Free article.

7

A PEGylated analog of the gut hormone oxyntomodulin with long-lasting antihyperglycemic, insulinotropic and anorexigenic activity.

Bianchi E, Carrington PE, Ingallinella P, Finotto M, Santoprete A, Petrov A, Eiermann G, Kosinski J, Marsh DJ, Pocai A, SinhaRoy R, Pessi A. Bianchi E, et al. Bioorg Med Chem. 2013 Nov 15;21(22):7064-73. doi: 10.1016/j.bmc.2013.09.016. Epub 2013 Sep 19. Bioorg Med Chem. 2013. PMID: 24094437

8

A novel nonpeptide HIV-1 protease inhibitor: elucidation of the binding mode and its application in the design of related analogs.

Lunney EA, Hagen SE, Domagala JM, Humblet C, Kosinski J, Tait BD, Warmus JS, Wilson M, Ferguson D, Hupe D, et al. Lunney EA, et al. J Med Chem. 1994 Aug 19;37(17):2664-77. doi: 10.1021/jm00043a006. J Med Chem. 1994. PMID: 8064795

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