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Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models.
Su J, Brunner L, Ates Oz E, Sacherl J, Frank G, Kerth HA, Thiele F, Wiegand M, Mogler C, Aguilar JC, Knolle PA, Collin N, Kosinska AD, Protzer U. Su J, et al. Among authors: kosinska ad. J Hepatol. 2023 Apr;78(4):717-730. doi: 10.1016/j.jhep.2022.12.013. Epub 2023 Jan 9. J Hepatol. 2023. PMID: 36634821 Free article.
Therapeutic vaccination for chronic hepatitis B.
Kosinska AD, Bauer T, Protzer U. Kosinska AD, et al. Curr Opin Virol. 2017 Apr;23:75-81. doi: 10.1016/j.coviro.2017.03.011. Epub 2017 Apr 25. Curr Opin Virol. 2017. PMID: 28453967 Review.
Amino Acid Substitutions within HLA-B*27-Restricted T Cell Epitopes Prevent Recognition by Hepatitis Delta Virus-Specific CD8+ T Cells.
Karimzadeh H, Kiraithe MM, Kosinska AD, Glaser M, Fiedler M, Oberhardt V, Salimi Alizei E, Hofmann M, Mok JY, Nguyen M, van Esch WJE, Budeus B, Grabowski J, Homs M, Olivero A, Keyvani H, Rodríguez-Frías F, Tabernero D, Buti M, Heinold A, Alavian SM, Bauer T, Schulze Zur Wiesch J, Raziorrouh B, Hoffmann D, Smedile A, Rizzetto M, Wedemeyer H, Timm J, Antes I, Neumann-Haefelin C, Protzer U, Roggendorf M. Karimzadeh H, et al. Among authors: kosinska ad. J Virol. 2018 Jun 13;92(13):e01891-17. doi: 10.1128/JVI.01891-17. Print 2018 Jul 1. J Virol. 2018. PMID: 29669837 Free PMC article.
Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, Knolle P, Protzer U. Michler T, et al. Among authors: kosinska ad. Gastroenterology. 2020 May;158(6):1762-1775.e9. doi: 10.1053/j.gastro.2020.01.032. Epub 2020 Jan 28. Gastroenterology. 2020. PMID: 32001321
34 results