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Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: kosik i. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
Defining B cell immunodominance to viruses.
Angeletti D, Gibbs JS, Angel M, Kosik I, Hickman HD, Frank GM, Das SR, Wheatley AK, Prabhakaran M, Leggat DJ, McDermott AB, Yewdell JW. Angeletti D, et al. Among authors: kosik i. Nat Immunol. 2017 Apr;18(4):456-463. doi: 10.1038/ni.3680. Epub 2017 Feb 13. Nat Immunol. 2017. PMID: 28192417 Free PMC article.
Influenza A Virus Negative Strand RNA Is Translated for CD8+ T Cell Immunosurveillance.
Hickman HD, Mays JW, Gibbs J, Kosik I, Magadán JG, Takeda K, Das S, Reynoso GV, Ngudiankama BF, Wei J, Shannon JP, McManus D, Yewdell JW. Hickman HD, et al. Among authors: kosik i. J Immunol. 2018 Aug 15;201(4):1222-1228. doi: 10.4049/jimmunol.1800586. Epub 2018 Jul 16. J Immunol. 2018. PMID: 30012850 Free PMC article.
Outflanking immunodominance to target subdominant broadly neutralizing epitopes.
Angeletti D, Kosik I, Santos JJS, Yewdell WT, Boudreau CM, Mallajosyula VVA, Mankowski MC, Chambers M, Prabhakaran M, Hickman HD, McDermott AB, Alter G, Chaudhuri J, Yewdell JW. Angeletti D, et al. Among authors: kosik i. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13474-13479. doi: 10.1073/pnas.1816300116. Epub 2019 Jun 18. Proc Natl Acad Sci U S A. 2019. PMID: 31213541 Free PMC article.
50 results