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226 results

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Page 1
Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.
Toledo MAS, Gatz M, Sontag S, Gleixner KV, Eisenwort G, Feldberg K, Hamouda AEI, Kluge F, Guareschi R, Rossetti G, Sechi AS, Dufva OMJ, Mustjoki SM, Maurer A, Schüler HM, Goetzke R, Braunschweig T, Kaiser A, Panse J, Jawhar M, Reiter A, Hilberg F, Ettmayer P, Wagner W, Koschmieder S, Brümmendorf TH, Valent P, Chatain N, Zenke M. Toledo MAS, et al. Among authors: koschmieder s. Blood. 2021 Apr 15;137(15):2070-2084. doi: 10.1182/blood.2019004509. Blood. 2021. PMID: 33512435 Free article.
Flt3-dependent transformation by inactivating c-Cbl mutations in AML.
Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Müller-Tidow C, Dikic I, Serve H. Sargin B, et al. Among authors: koschmieder s. Blood. 2007 Aug 1;110(3):1004-12. doi: 10.1182/blood-2007-01-066076. Epub 2007 Apr 19. Blood. 2007. PMID: 17446348 Free article. Clinical Trial.
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.
Schemionek M, Elling C, Steidl U, Bäumer N, Hamilton A, Spieker T, Göthert JR, Stehling M, Wagers A, Huettner CS, Tenen DG, Tickenbrock L, Berdel WE, Serve H, Holyoake TL, Müller-Tidow C, Koschmieder S. Schemionek M, et al. Among authors: koschmieder s. Blood. 2010 Apr 22;115(16):3185-95. doi: 10.1182/blood-2009-04-215376. Epub 2010 Jan 6. Blood. 2010. PMID: 20053753 Free PMC article.
Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model.
Agrawal-Singh S, Koschmieder S, Gelsing S, Stocking C, Stehling M, Thiede C, Thoennissen NH, Köhler G, Valk PJ, Delwel R, Mills K, Bäumer N, Tickenbrock L, Hansen K, Berdel WE, Müller-Tidow C, Serve H. Agrawal-Singh S, et al. Among authors: koschmieder s. Blood. 2010 Jun 3;115(22):4507-16. doi: 10.1182/blood-2009-03-210070. Epub 2010 Mar 9. Blood. 2010. PMID: 20215640 Free article.
Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease.
Elling C, Erben P, Walz C, Frickenhaus M, Schemionek M, Stehling M, Serve H, Cross NC, Hochhaus A, Hofmann WK, Berdel WE, Müller-Tidow C, Reiter A, Koschmieder S. Elling C, et al. Among authors: koschmieder s. Blood. 2011 Mar 10;117(10):2935-43. doi: 10.1182/blood-2010-05-286757. Epub 2011 Jan 11. Blood. 2011. PMID: 21224473 Free article.
AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein.
Steffen B, Knop M, Bergholz U, Vakhrusheva O, Rode M, Köhler G, Henrichs MP, Bulk E, Hehn S, Stehling M, Dugas M, Bäumer N, Tschanter P, Brandts C, Koschmieder S, Berdel WE, Serve H, Stocking C, Müller-Tidow C. Steffen B, et al. Among authors: koschmieder s. Blood. 2011 Apr 21;117(16):4328-37. doi: 10.1182/blood-2009-09-242545. Epub 2011 Jan 18. Blood. 2011. PMID: 21245488 Free article.
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene.
Agrawal-Singh S, Isken F, Agelopoulos K, Klein HU, Thoennissen NH, Koehler G, Hascher A, Bäumer N, Berdel WE, Thiede C, Ehninger G, Becker A, Schlenke P, Wang Y, McClelland M, Krug U, Koschmieder S, Büchner T, Yu DY, Singh SV, Hansen K, Serve H, Dugas M, Müller-Tidow C. Agrawal-Singh S, et al. Among authors: koschmieder s. Blood. 2012 Mar 8;119(10):2346-57. doi: 10.1182/blood-2011-06-358705. Epub 2011 Dec 29. Blood. 2012. PMID: 22207736 Free article.
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells.
Bolton-Gillespie E, Schemionek M, Klein HU, Flis S, Hoser G, Lange T, Nieborowska-Skorska M, Maier J, Kerstiens L, Koptyra M, Müller MC, Modi H, Stoklosa T, Seferynska I, Bhatia R, Holyoake TL, Koschmieder S, Skorski T. Bolton-Gillespie E, et al. Among authors: koschmieder s. Blood. 2013 May 16;121(20):4175-83. doi: 10.1182/blood-2012-11-466938. Epub 2013 Mar 29. Blood. 2013. PMID: 23543457 Free PMC article.
Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.
Jost E, Lin Q, Weidner CI, Wilop S, Hoffmann M, Walenda T, Schemionek M, Herrmann O, Zenke M, Brümmendorf TH, Koschmieder S, Wagner W. Jost E, et al. Among authors: koschmieder s. Leukemia. 2014 Jun;28(6):1227-34. doi: 10.1038/leu.2013.362. Epub 2013 Nov 27. Leukemia. 2014. PMID: 24280869 Free PMC article.
226 results