Korabecny J - Search Results

1

Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.

Makhaeva GF, Kovaleva NV, Boltneva NP, Rudakova EV, Lushchekina SV, Astakhova TY, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Korabecny J, Soukup O, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: korabecny j. Molecules. 2022 Feb 4;27(3):1060. doi: 10.3390/molecules27031060. Molecules. 2022. PMID: 35164325 Free PMC article.

2

Preparation of the pyridinium salts differing in the length of the N-alkyl substituent.

Marek J, Stodulka P, Cabal J, Soukup O, Pohanka M, Korabecny J, Musilek K, Kuca K. Marek J, et al. Among authors: korabecny j. Molecules. 2010 Mar 19;15(3):1967-72. doi: 10.3390/molecules15031967. Molecules. 2010. PMID: 20336025 Free PMC article.

3

Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.

Korabecny J, Musilek K, Holas O, Binder J, Zemek F, Marek J, Pohanka M, Opletalova V, Dohnal V, Kuca K. Korabecny J, et al. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6093-5. doi: 10.1016/j.bmcl.2010.08.044. Epub 2010 Aug 16. Bioorg Med Chem Lett. 2010. PMID: 20817518

4

Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment.

Korabecny J, Musilek K, Holas O, Nepovimova E, Jun D, Zemek F, Opletalova V, Patocka J, Dohnal V, Nachon F, Hroudova J, Fisar Z, Kuca K. Korabecny J, et al. Molecules. 2010 Dec 2;15(12):8804-12. doi: 10.3390/molecules15128804. Molecules. 2010. PMID: 21127466 Free PMC article.

5

[Intended pharmacotherapeutical approaches of Alzheimer's disease therapy].

Korábecný J, Hrubá E, Soukup O, Zemek F, Musílek K, Nepovímová E, Spilovská K, Opletalová V, Kuca K. Korábecný J, et al. Ceska Slov Farm. 2012 Feb;61(1-2):4-10. Ceska Slov Farm. 2012. PMID: 22536646 Review. Czech.

6

[Tacrine and its derivatives in the therapy of Alzheimers disease].

Korábečný J, Spilovská K, Benek O, Musílek K, Soukup O, Kuča K. Korábečný J, et al. Ceska Slov Farm. 2012 Oct;61(5):210-21. Ceska Slov Farm. 2012. PMID: 23256654 Review. Czech.

7

7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.

Spilovska K, Korabecny J, Kral J, Horova A, Musilek K, Soukup O, Drtinova L, Gazova Z, Siposova K, Kuca K. Spilovska K, et al. Among authors: korabecny j. Molecules. 2013 Feb 20;18(2):2397-418. doi: 10.3390/molecules18022397. Molecules. 2013. PMID: 23429378 Free PMC article.

8

Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) study.

Sepsova V, Karasova JZ, Korabecny J, Dolezal R, Zemek F, Bennion BJ, Kuca K. Sepsova V, et al. Among authors: korabecny j. Int J Mol Sci. 2013 Aug 16;14(8):16882-900. doi: 10.3390/ijms140816882. Int J Mol Sci. 2013. PMID: 23959117 Free PMC article.

9

A resurrection of 7-MEOTA: a comparison with tacrine.

Soukup O, Jun D, Zdarova-Karasova J, Patocka J, Musilek K, Korabecny J, Krusek J, Kaniakova M, Sepsova V, Mandikova J, Trejtnar F, Pohanka M, Drtinova L, Pavlik M, Tobin G, Kuca K. Soukup O, et al. Among authors: korabecny j. Curr Alzheimer Res. 2013 Oct;10(8):893-906. doi: 10.2174/1567205011310080011. Curr Alzheimer Res. 2013. PMID: 24093535

10

From pyridinium-based to centrally active acetylcholinesterase reactivators.

Korabecny J, Soukup O, Dolezal R, Spilovska K, Nepovimova E, Andrs M, Nguyen TD, Jun D, Musilek K, Kucerova-Chlupacova M, Kuca K. Korabecny J, et al. Mini Rev Med Chem. 2014;14(3):215-21. doi: 10.2174/1389557514666140219103138. Mini Rev Med Chem. 2014. PMID: 24552265 Review.

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