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YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H. Tanaka H, et al. Among authors: kondo k. Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. Nat Commun. 2020. PMID: 31980612 Free PMC article.
The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology.
Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, Aoki S, Saito T, Saido T, Muramatsu SI, Fujita K, Okazawa H. Tanaka H, et al. Among authors: kondo k. Mol Psychiatry. 2018 Oct;23(10):2090-2110. doi: 10.1038/s41380-018-0253-8. Epub 2018 Oct 3. Mol Psychiatry. 2018. PMID: 30283027 Free PMC article.
Methods to Image Macroautophagy in the Brain In Vivo.
Chen X, Kondo K, Okazawa H. Chen X, et al. Among authors: kondo k. Methods Mol Biol. 2019;1880:529-534. doi: 10.1007/978-1-4939-8873-0_33. Methods Mol Biol. 2019. PMID: 30610719
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Homma H, Tanaka H, Jin M, Jin X, Huang Y, Yoshioka Y, Bertens CJ, Tsumaki K, Kondo K, Shiwaku H, Tagawa K, Akatsu H, Atsuta N, Katsuno M, Furukawa K, Ishiki A, Waragai M, Ohtomo G, Iwata A, Yokota T, Inoue H, Arai H, Sobue G, Sone M, Fujita K, Okazawa H. Homma H, et al. Among authors: kondo k. Life Sci Alliance. 2021 Jun 15;4(7):e202101022. doi: 10.26508/lsa.202101022. Print 2021 Jul. Life Sci Alliance. 2021. PMID: 34130995 Free PMC article.
Hepta-Histidine Inhibits Tau Aggregation.
Kondo K, Ikura T, Tanaka H, Fujita K, Takayama S, Yoshioka Y, Tagawa K, Homma H, Liu S, Kawasaki R, Huang Y, Ito N, Tate SI, Okazawa H. Kondo K, et al. ACS Chem Neurosci. 2021 Aug 18;12(16):3015-3027. doi: 10.1021/acschemneuro.1c00164. Epub 2021 Jul 28. ACS Chem Neurosci. 2021. PMID: 34319089
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology.
Tanaka H, Kondo K, Fujita K, Homma H, Tagawa K, Jin X, Jin M, Yoshioka Y, Takayama S, Masuda H, Tokuyama R, Nakazaki Y, Saito T, Saido T, Murayama S, Ikura T, Ito N, Yamamori Y, Tomii K, Bianchi ME, Okazawa H. Tanaka H, et al. Among authors: kondo k. Commun Biol. 2021 Oct 11;4(1):1175. doi: 10.1038/s42003-021-02671-4. Commun Biol. 2021. PMID: 34635772 Free PMC article.
4,237 results