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ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. Haemmerle G, et al. Among authors: kolb d. Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439. Nat Med. 2011. PMID: 21857651 Free PMC article.
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: kolb d. J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424161 Free PMC article.
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
Aflaki E, Radovic B, Chandak PG, Kolb D, Eisenberg T, Ring J, Fertschai I, Uellen A, Wolinski H, Kohlwein SD, Zechner R, Levak-Frank S, Sattler W, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: kolb d. J Biol Chem. 2011 Mar 4;286(9):7418-28. doi: 10.1074/jbc.M110.175703. Epub 2011 Jan 1. J Biol Chem. 2011. PMID: 21196579 Free PMC article.
Remodeling of lipid droplets during lipolysis and growth in adipocytes.
Paar M, Jüngst C, Steiner NA, Magnes C, Sinner F, Kolb D, Lass A, Zimmermann R, Zumbusch A, Kohlwein SD, Wolinski H. Paar M, et al. Among authors: kolb d. J Biol Chem. 2012 Mar 30;287(14):11164-73. doi: 10.1074/jbc.M111.316794. Epub 2012 Feb 6. J Biol Chem. 2012. PMID: 22311986 Free PMC article.
C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Aflaki E, Doddapattar P, Radović B, Povoden S, Kolb D, Vujić N, Wegscheider M, Koefeler H, Hornemann T, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: kolb d. Cell Death Dis. 2012 Mar 15;3(3):e280. doi: 10.1038/cddis.2012.17. Cell Death Dis. 2012. PMID: 22419109 Free PMC article.
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.
Pollak NM, Schweiger M, Jaeger D, Kolb D, Kumari M, Schreiber R, Kolleritsch S, Markolin P, Grabner GF, Heier C, Zierler KA, Rülicke T, Zimmermann R, Lass A, Zechner R, Haemmerle G. Pollak NM, et al. Among authors: kolb d. J Lipid Res. 2013 Apr;54(4):1092-102. doi: 10.1194/jlr.M034710. Epub 2013 Jan 23. J Lipid Res. 2013. PMID: 23345410 Free PMC article.
Functional cardiac lipolysis in mice critically depends on comparative gene identification-58.
Zierler KA, Jaeger D, Pollak NM, Eder S, Rechberger GN, Radner FPW, Woelkart G, Kolb D, Schmidt A, Kumari M, Preiss-Landl K, Pieske B, Mayer B, Zimmermann R, Lass A, Zechner R, Haemmerle G. Zierler KA, et al. Among authors: kolb d. J Biol Chem. 2013 Apr 5;288(14):9892-9904. doi: 10.1074/jbc.M112.420620. Epub 2013 Feb 14. J Biol Chem. 2013. PMID: 23413028 Free PMC article.
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Doddapattar P, Radović B, Patankar JV, Obrowsky S, Jandl K, Nusshold C, Kolb D, Vujić N, Doshi L, Chandak PG, Goeritzer M, Ahammer H, Hoefler G, Sattler W, Kratky D. Doddapattar P, et al. Among authors: kolb d. Mol Nutr Food Res. 2013 Oct;57(10):1718-28. doi: 10.1002/mnfr.201200794. Epub 2013 May 3. Mol Nutr Food Res. 2013. PMID: 23650230 Free PMC article.
NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Pessentheiner AR, Pelzmann HJ, Walenta E, Schweiger M, Groschner LN, Graier WF, Kolb D, Uno K, Miyazaki T, Nitta A, Rieder D, Prokesch A, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: kolb d. J Biol Chem. 2013 Dec 13;288(50):36040-51. doi: 10.1074/jbc.M113.491324. Epub 2013 Oct 23. J Biol Chem. 2013. PMID: 24155240 Free PMC article.
200 results