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Characterization of a robust mouse model of heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H203-H231. doi: 10.1152/ajpheart.00038.2023. Epub 2023 May 19.
Am J Physiol Heart Circ Physiol. 2023.
PMID: 37204871
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury.
Ranek MJ, Oeing C, Sanchez-Hodge R, Kokkonen-Simon KM, Dillard D, Aslam MI, Rainer PP, Mishra S, Dunkerly-Eyring B, Holewinski RJ, Virus C, Zhang H, Mannion MM, Agrawal V, Hahn V, Lee DI, Sasaki M, Van Eyk JE, Willis MS, Page RC, Schisler JC, Kass DA.
Ranek MJ, et al. Among authors: kokkonen simon km.
Nat Commun. 2020 Oct 20;11(1):5237. doi: 10.1038/s41467-020-18980-x.
Nat Commun. 2020.
PMID: 33082318
Free PMC article.
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PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy.
Oeing CU, Nakamura T, Pan S, Mishra S, Dunkerly-Eyring BL, Kokkonen-Simon KM, Lin BL, Chen A, Zhu G, Bedja D, Lee DI, Kass DA, Ranek MJ.
Oeing CU, et al. Among authors: kokkonen simon km.
Circ Res. 2020 Jul 31;127(4):522-533. doi: 10.1161/CIRCRESAHA.119.315714. Epub 2020 May 12.
Circ Res. 2020.
PMID: 32393148
Free PMC article.
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PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.
Ranek MJ, Kokkonen-Simon KM, Chen A, Dunkerly-Eyring BL, Vera MP, Oeing CU, Patel CH, Nakamura T, Zhu G, Bedja D, Sasaki M, Holewinski RJ, Van Eyk JE, Powell JD, Lee DI, Kass DA.
Ranek MJ, et al. Among authors: kokkonen simon km.
Nature. 2019 Feb;566(7743):264-269. doi: 10.1038/s41586-019-0895-y. Epub 2019 Jan 30.
Nature. 2019.
PMID: 30700906
Free PMC article.
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Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis.
Zhang QJ, Tran TAT, Wang M, Ranek MJ, Kokkonen-Simon KM, Gao J, Luo X, Tan W, Kyrychenko V, Liao L, Xu J, Hill JA, Olson EN, Kass DA, Martinez ED, Liu ZP.
Zhang QJ, et al. Among authors: kokkonen simon km.
Nat Commun. 2018 Dec 7;9(1):5230. doi: 10.1038/s41467-018-07173-2.
Nat Commun. 2018.
PMID: 30531796
Free PMC article.
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Marked disparity of microRNA modulation by cGMP-selective PDE5 versus PDE9 inhibitors in heart disease.
Kokkonen-Simon KM, Saberi A, Nakamura T, Ranek MJ, Zhu G, Bedja D, Kuhn M, Halushka MK, Lee DI, Kass DA.
Kokkonen-Simon KM, et al.
JCI Insight. 2018 Aug 9;3(15):e121739. doi: 10.1172/jci.insight.121739. eCollection 2018 Aug 9.
JCI Insight. 2018.
PMID: 30089721
Free PMC article.
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Prevention of PKG-1α Oxidation Suppresses Antihypertrophic/Antifibrotic Effects From PDE5 Inhibition but not sGC Stimulation.
Nakamura T, Zhu G, Ranek MJ, Kokkonen-Simon K, Zhang M, Kim GE, Tsujita K, Kass DA.
Nakamura T, et al. Among authors: kokkonen simon k.
Circ Heart Fail. 2018 Mar;11(3):e004740. doi: 10.1161/CIRCHEARTFAILURE.117.004740.
Circ Heart Fail. 2018.
PMID: 29545395
Free PMC article.
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Right Ventricular Myofilament Functional Differences in Humans With Systemic Sclerosis-Associated Versus Idiopathic Pulmonary Arterial Hypertension.
Hsu S, Kokkonen-Simon KM, Kirk JA, Kolb TM, Damico RL, Mathai SC, Mukherjee M, Shah AA, Wigley FM, Margulies KB, Hassoun PM, Halushka MK, Tedford RJ, Kass DA.
Hsu S, et al. Among authors: kokkonen simon km.
Circulation. 2018 May 29;137(22):2360-2370. doi: 10.1161/CIRCULATIONAHA.117.033147. Epub 2018 Jan 19.
Circulation. 2018.
PMID: 29352073
Free PMC article.
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